RNA14_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RNA14_SCHPO
• UniProt AC: O14233
• Protein Name: mRNA 3'-end-processing protein rna14
• Gene Name: rna14
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 733
• Subcellular Localization: Nucleus. Cytoplasm. Nucleus and/or cytoplasm..
• Protein Description: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation..
• Protein Sequence: MNSDDNVEADASSNIIKDSPKIKEQENTSTVNESDVLATSTTASSGVKRKRLPNDLVGQLRDKIQENPNDISSWYALVEEYGSKGKHEELRETYEQMLRPFPYVPRVWVDYISSELAFNDFHAVELLFSRCLVKVLSVDLWTLYLSYIRRINPDGEGQSRSTITQAYEFVINTIGVDILSGPIWSEFVDFLRSGPANSTWEQQQKLDHVRRIYQRAITTPIHNIEKLWRDYDAFENSVNRATARKFVAEKSPVYMAARAAMRELSNLTEGLRVYDFTFERKYTKVERIAYSRWMNWIKWEQSDPLDLQHGTMLQNRIAYAFEQAMLYVPLCPQIWLDGFSYFLSISDEQRALQTIRRGMRYCPSNFVLHVRYAEHEEANNRTSEIRSTYESLIAALAREISQLDSKASSSSESSTDGNPQEKKLPEHLVKRKSRLVRQYSLAWCCLINAIRRTEGVKAARAIFTKARKAPYQSHEIYIASAMMEHHCSRDPVIASRIFELGMRHFGDVPAYVYKYLSYLIAINDETNARALFEKAIPRIAADEAKPIYQKWLDYESNYGDLNAAIALSQRMAVVYPQESTQAIFLSRYGLKDDAEEEERETKEAEKIRELSVRLNGGNGFPGHVHNNREDDEVSIASTSSKSNVEMEDTRLLPASLELANTQGASNPPTSALPTVPVPLPSIITEFLDELPAPQVITGPRIQPTKLIDHIIKSDIPFIRLRNANAHLKRARFN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MNSDDNVEAD -----CCCCCCCCCC	45.07	24763107
12	Phosphorylation	DNVEADASSNIIKDS CCCCCCCCCCCCCCC	25.19	24763107
13	Phosphorylation	NVEADASSNIIKDSP CCCCCCCCCCCCCCC	33.49	28889911
19	Phosphorylation	SSNIIKDSPKIKEQE CCCCCCCCCCCCCCC	24.08	28889911
28	Phosphorylation	KIKEQENTSTVNESD CCCCCCCCCCCCHHH	25.64	29996109
29	Phosphorylation	IKEQENTSTVNESDV CCCCCCCCCCCHHHH	41.77	29996109
611	Phosphorylation	AEKIRELSVRLNGGN HHHHHHHHCCCCCCC	10.63	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RNA14_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RNA14_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RNA14_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MIS12_SCHPO	mis12	genetic	26581324
BUB1_SCHPO	bub1	genetic	26581324
MAD2_SCHPO	mad2	genetic	26581324

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.