RL28_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL28_MOUSE
• UniProt AC: P41105
• Protein Name: 60S ribosomal protein L28
• Gene Name: Rpl28
• Organism: Mus musculus (Mouse).
• Sequence Length: 137
• Protein Description: Component of the large ribosomal subunit..
• Protein Sequence: MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVMKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMAAIRRASAILRSQKPVVVKRKRTRPTKSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSAHLQWMV ------CCHHHHHHH	25.13	29514104
2	Acetylation	------MSAHLQWMV ------CCHHHHHHH	25.13	-
13	S-palmitoylation	QWMVVRNCSSFLIKR HHHHHCCCHHHHECC	2.24	28526873
13	Glutathionylation	QWMVVRNCSSFLIKR HHHHHCCCHHHHECC	2.24	24333276
15	Phosphorylation	MVVRNCSSFLIKRNK HHHCCCHHHHECCCC	26.69	27841257
19	Acetylation	NCSSFLIKRNKQTYS CCHHHHECCCCCCCC	52.65	23806337
22	Succinylation	SFLIKRNKQTYSTEP HHHECCCCCCCCCCC	48.31	23806337
22	Acetylation	SFLIKRNKQTYSTEP HHHECCCCCCCCCCC	48.31	23806337
25	Phosphorylation	IKRNKQTYSTEPNNL ECCCCCCCCCCCCCC	15.88	29514104
33	Ubiquitination	STEPNNLKARNSFRY CCCCCCCCCCCCEEE	47.63	-
33	Succinylation	STEPNNLKARNSFRY CCCCCCCCCCCCEEE	47.63	23806337
33	Acetylation	STEPNNLKARNSFRY CCCCCCCCCCCCEEE	47.63	23806337
37	Phosphorylation	NNLKARNSFRYNGLI CCCCCCCCEEECCEE	12.92	-
47	Ubiquitination	YNGLIHRKTVGVEPA ECCEEEEEEEEEEEC	33.14	22790023
58	Ubiquitination	VEPAADGKGVVVVMK EEECCCCCEEEEEEE	49.43	22790023
68	Phosphorylation	VVVMKRRSGQRKPAT EEEEECCCCCCCCCC	43.22	29514104
72	Ubiquitination	KRRSGQRKPATSYVR ECCCCCCCCCCEEEE	30.99	22790023
76	Phosphorylation	GQRKPATSYVRTTIN CCCCCCCEEEEECCC	24.60	25338131
77	Phosphorylation	QRKPATSYVRTTINK CCCCCCEEEEECCCC	6.92	29514104
84	Acetylation	YVRTTINKNARATLS EEEECCCCCHHHHHH	48.40	22826441
84	Ubiquitination	YVRTTINKNARATLS EEEECCCCCHHHHHH	48.40	-
89	Phosphorylation	INKNARATLSSIRHM CCCCHHHHHHHHHHH	22.94	29514104
91	Phosphorylation	KNARATLSSIRHMIR CCHHHHHHHHHHHHH	21.26	25159016
92	Phosphorylation	NARATLSSIRHMIRK CHHHHHHHHHHHHHH	27.10	25159016
115	Phosphorylation	MAAIRRASAILRSQK HHHHHHHHHHHHCCC	17.65	26824392
122	Acetylation	SAILRSQKPVVVKRK HHHHHCCCCEEEEEE	40.81	23201123
131	Phosphorylation	VVVKRKRTRPTKSS- EEEEEECCCCCCCC-	43.99	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL28_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL28_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL28_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IF6_MOUSE	Eif6	physical	21536732
SBDS_MOUSE	Sbds	physical	21536732
EFNA1_MOUSE	Efna1	physical	21536732

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.