dbPTM

RL17_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RL17_DROME
UniProt AC	Q9W3W8
Protein Name	60S ribosomal protein L17
Gene Name	RpL17
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	186
Subcellular Localization
Protein Description
Protein Sequence	MGRYSRESDNVAKSCKARGPNLRVHFKNTHETAQAIKRMPLRRAQRYLKAVIDQKECVPFRRFNGGVGRCAQAKQWKTTQGRWPKKSAEFLLQLLRNAEANADCKGLDADRLVVHHIQVNRAQCLRRRTYRAHGRINPYMSSPCHVEVILTEKEELVSKATDDEPAKKKLSKKKLQRQKEKMLRSE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MGRYSRESDNV ----CCCCCCCHHHH	13.32	19429919
5	Phosphorylation	---MGRYSRESDNVA ---CCCCCCCHHHHH	28.36	19429919
8	Phosphorylation	MGRYSRESDNVAKSC CCCCCCCHHHHHHHH	33.12	19429919
37	Acetylation	HETAQAIKRMPLRRA HHHHHHHHHCHHHHH	45.73	21791702
142	Phosphorylation	RINPYMSSPCHVEVI CCCCCCCCCCEEEEE	18.28	21082442
158	Phosphorylation	TEKEELVSKATDDEP CCHHHHHHHCCCCHH	29.24	22817900
159	Acetylation	EKEELVSKATDDEPA CHHHHHHHCCCCHHH	48.07	21791702
161	Phosphorylation	EELVSKATDDEPAKK HHHHHHCCCCHHHHH	47.95	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RL17_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RL17_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RL17_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
DORS_DROME	dl	physical	14605208
DIMM_DROME	dimm	physical	14605208

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RL17_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-158 AND THR-161, ANDMASS SPECTROMETRY.	18327897 [Abstract]