RBP17_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RBP17_HUMAN
• UniProt AC: Q9H2T7
• Protein Name: Ran-binding protein 17
• Gene Name: RANBP17
• Organism: Homo sapiens (Human).
• Sequence Length: 1088
• Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nuclear pore complex.
• Protein Description: May function as a nuclear transport receptor..
• Protein Sequence: MALHFQSLAELEVLCTHLYIGTDLTQRIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVSRVSPLPVEQRMDIRNYILNYVASQPKLAPFVIQALIQVIAKITKLGWFEVQKDQFVFREIIADVKKFLQGTVEHCIIGVIILSELTQEMNLVDYSRPSAKHRKIATSFRDTSLKDVLVLACSLLKEVFAKPLNLQDQCQQNLVMQVLKLVLNCLNFDFIGSSADESADDLCTVQIPTTWRTIFLEPETLDLFFNLYHSLPPLLSQLALSCLVQFASTRRSLFNSPERAKYLGNLIKGVKRILENPQGLSDPGNYHEFCRFLARLKTNYQLGELVMVKEYPEVIRLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPFVKSTEPHLLDTYAPEITKAFITSRLDSVAIVVRDHLDDPLDDTATVFQQLEQLCTVSRCEYEKTCALLVQLFDQNAQNYQKLLHPYSGVTVDITIQEGRLAWLVYLVGTVVGGRLTYTSTDEHDAMDGELSCRVFQLISLMDTGLPRCCNEKIELAILWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRYEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDNHSLSDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVAFETVLQIFNNNFKQEDVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMYPTYLPLLQNAVERWYGEPTCTTPILKLMAELMQNRSQRLNFDVSSPNGILLFREASKMVCTYGNQILSLGSLSKDQIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTLDTVVSSSCCTSLDYIVTYLFKHIAKEGKKPLRCREATQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLAQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRSDGNTEPCSLDMMS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MALHFQSLA ------CCCHHHCHH	22.50	-
19	Phosphorylation	EVLCTHLYIGTDLTQ HHHHHHHHCCCCHHH	6.95	26503514
22	Phosphorylation	CTHLYIGTDLTQRIE HHHHHCCCCHHHHHH	20.48	26503514
25	Phosphorylation	LYIGTDLTQRIEAEK HHCCCCHHHHHHHHH	20.72	26503514
92	Phosphorylation	IRNYILNYVASQPKL HHHHHHHHHHCCCCH	8.24	20068231
95	Phosphorylation	YILNYVASQPKLAPF HHHHHHHCCCCHHHH	36.65	20068231
178	Phosphorylation	AKHRKIATSFRDTSL HHHHHHHHHCCCCCH	31.69	20068231
179	Phosphorylation	KHRKIATSFRDTSLK HHHHHHHHCCCCCHH	14.84	20068231
183	Phosphorylation	IATSFRDTSLKDVLV HHHHCCCCCHHHHHH	31.53	20068231
184	Phosphorylation	ATSFRDTSLKDVLVL HHHCCCCCHHHHHHH	37.40	20068231
194	Phosphorylation	DVLVLACSLLKEVFA HHHHHHHHHHHHHHC	31.00	24719451
296	Phosphorylation	TRRSLFNSPERAKYL HCHHHHCCHHHHHHH	22.32	23312004
389	O-linked_Glycosylation	LWQRMVASVPFVKST HHHHHHHCCCCCCCC	20.93	30379171
395	Phosphorylation	ASVPFVKSTEPHLLD HCCCCCCCCCCCHHH	32.47	29083192
396	Phosphorylation	SVPFVKSTEPHLLDT CCCCCCCCCCCHHHC	48.06	29083192
403	Phosphorylation	TEPHLLDTYAPEITK CCCCHHHCCCHHHHH	22.88	29083192
404	Phosphorylation	EPHLLDTYAPEITKA CCCHHHCCCHHHHHH	21.59	29083192
409	Phosphorylation	DTYAPEITKAFITSR HCCCHHHHHHHHHHC	18.04	29083192
410	Ubiquitination	TYAPEITKAFITSRL CCCHHHHHHHHHHCC	47.14	21906983
414	Phosphorylation	EITKAFITSRLDSVA HHHHHHHHHCCCEEE	11.01	29083192
415	Phosphorylation	ITKAFITSRLDSVAI HHHHHHHHCCCEEEE	26.48	29083192
471	Phosphorylation	FDQNAQNYQKLLHPY HHHCHHHHHHHHCCC	8.57	25332170
501	Phosphorylation	WLVYLVGTVVGGRLT HHHHHHCCEECCEEE	12.44	20068231
560	Phosphorylation	LDQFRKTYVGDQLQR HHHHHHHCCHHHHHH	12.89	20068231
569	Phosphorylation	GDQLQRTSKVYARMS HHHHHHHHHHHHHHH	23.47	20068231
572	Phosphorylation	LQRTSKVYARMSEVL HHHHHHHHHHHHHHH	7.69	22817900
620	Phosphorylation	LQFLNDLSVGYILLK HHHHHHCCHHHHHHH	19.16	20058876
745	Phosphorylation	TMLFDWMYPTYLPLL HHHHCCCCCCHHHHH	6.54	25849741
767	Phosphorylation	YGEPTCTTPILKLMA HCCCCCCHHHHHHHH	15.52	24719451
806	Phosphorylation	EASKMVCTYGNQILS ECCCCEEECCCEEEE	24.05	-
823	Phosphorylation	SLSKDQIYPMKLKGI CCCCCCEECCCCCHH	7.52	-
834	Phosphorylation	LKGISICYSALKSAL CCHHHHHHHHHHHHH	8.70	22461510
835	Phosphorylation	KGISICYSALKSALC CHHHHHHHHHHHHHC	23.78	24719451
854	Phosphorylation	SFGVFKLYGDNHFDN EEEEEHHHCCCCHHH	24.03	-
872	Phosphorylation	AFVKMLLSVSHSDLL HHHHHHHCCCHHHHH	20.01	25072903
874	Phosphorylation	VKMLLSVSHSDLLQY HHHHHCCCHHHHHHH	17.56	25072903
876	Phosphorylation	MLLSVSHSDLLQYRK HHHCCCHHHHHHHHH	23.58	25072903
881	Phosphorylation	SHSDLLQYRKLSQSY CHHHHHHHHHHHHHH	15.08	25072903
1017	Phosphorylation	LLNEKYFSELRASLI HHCHHHHHHHHHHHH	32.41	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RBP17_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RBP17_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RBP17_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VPS11_HUMAN	VPS11	physical	22939629
XPO6_HUMAN	XPO6	physical	22939629
SCAI_HUMAN	SCAI	physical	22939629
TPPC5_HUMAN	TRAPPC5	physical	22939629

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.