RASLC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RASLC_HUMAN
• UniProt AC: Q9NYN1
• Protein Name: Ras-like protein family member 12
• Gene Name: RASL12
• Organism: Homo sapiens (Human).
• Sequence Length: 266
• Protein Sequence: MSSVFGKPRAGSGPQSAPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDTPRNCERYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLGNKLDMAQYRQVTKAEGVALAGRFGCLFFEVSACLDFEHVQHVFHEAVREARRELEKSPLTRPLFISEERALPHQAPLTARHGLASCTFNTLSTINLKEMPTVAQAKLVTVKSSRAQSKRKAPTLTLLKGFKIF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	FGKPRAGSGPQSAPL CCCCCCCCCCCCCCE	46.44	26657352
34	Phosphorylation	GRRGAGKSALTVKFL CCCCCCCHHHHHHHH	27.82	23403867
37	Phosphorylation	GAGKSALTVKFLTKR CCCCHHHHHHHHHHH	22.74	23403867
189	Acetylation	EARRELEKSPLTRPL HHHHHHHHCCCCCCE	70.74	18530779
190	Phosphorylation	ARRELEKSPLTRPLF HHHHHHHCCCCCCEE	18.77	23312004
193	Phosphorylation	ELEKSPLTRPLFISE HHHHCCCCCCEEECC	33.36	23312004

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RASLC_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RASLC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RASLC_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
ARHGH_HUMAN	ARHGEF17	physical	26186194
FHL2_HUMAN	FHL2	physical	26186194
ARHGH_HUMAN	ARHGEF17	physical	28514442
FHL2_HUMAN	FHL2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.