dbPTM

ARHGH_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ARHGH_HUMAN
UniProt AC	Q96PE2
Protein Name	Rho guanine nucleotide exchange factor 17
Gene Name	ARHGEF17
Organism	Homo sapiens (Human).
Sequence Length	2063
Subcellular Localization
Protein Description	Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases..
Protein Sequence	MADGAPRPQLYRSVSFKLLERWSGGPGLREEDTDTPGLRRRASCRPTTAARGQPSRRVSKLASGPLAAPAQPRPLRSLSPSVRQLSRRFDAPRLDDGSAGTRDGGVLPAAAEEAAEGPARGAWPSVTEMRKLFGGPGSRRPSADSESPGTPSPDGAAWEPPARESRQPPTPPPRTCFPLAGLRSARPLTGPETEGRLRRPQQQQERAQRPADGLHSWHIFSQPQAGARASCSSSSIAASYPVSRSRAASSSEEEEEGPPQLPGAQSPAYHGGHSSGSDDDRDGEGGHRWGGRPGLRPGSSLLDQDCRPDSDGLNLSSMNSAGVSGSPEPPTSPRAPREEGLREWGSGSPPCVPGPQEGLRPMSDSVGGAFRVAKVSFPSYLASPAGSRGSSRYSSTETLKDDDLWSSRGSGGWGVYRSPSFGAGEGLLRSQARTRAKGPGGTSRALRDGGFEPEKSRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPVGQLEPIPIPAPASPGTRPTLKDLTATLRRAKSFTCSEKPMARRLPRTSALKSSSSELLLTGPGAEEDPLPLIVQDQYVQEARQVFEKIQRMGAQQDDGSDAPPGSPDWAGDVTRGQRSQEELSGPESSLTDEGIGADPEPPVAAFCGLGTTGMWRPLSSSSAQTNHHGPGTEDSLGGWALVSPETPPTPGALRRRRKVPPSGSGGSELSNGEAGEAYRSLSDPIPQRHRAATSEEPTGFSVDSNLLGSLSPKTGLPATSAMDEGLTSGHSDWSVGSEESKGYQEVIQSIVQGPGTLGRVVDDRIAGKAPKKKSLSDPSRRGELAGPGFEGPGGEPIREVEPMLPPSSSEPILVEQRAEPEEPGATRSRAQSERALPEALPPPATAHRNFHLDPKLADILSPRLIRRGSKKRPARSSHQELRRDEGSQDQTGSLSRARPSSRHVRHASVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYMLNLHSGEVPAPVPVDMPCLPLAAPPSAEAKPPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMTPGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREAGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQLPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSSGGGSSSETVGRDDSTNHLLLWRV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	PRPQLYRSVSFKLLE CCCHHHHHHHHHHHH	14.46	29514088
15	Phosphorylation	PQLYRSVSFKLLERW CHHHHHHHHHHHHHC	20.22	29514088
17	Acetylation	LYRSVSFKLLERWSG HHHHHHHHHHHHCCC	44.66	21466224
33	Phosphorylation	PGLREEDTDTPGLRR CCCCCCCCCCCCCCC	45.08	25850435
35	Phosphorylation	LREEDTDTPGLRRRA CCCCCCCCCCCCCHH	22.73	21815630
43	Phosphorylation	PGLRRRASCRPTTAA CCCCCHHCCCCCCCC	14.62	28348404
45	Methylation	LRRRASCRPTTAARG CCCHHCCCCCCCCCC	29.16	-
63	Phosphorylation	RRVSKLASGPLAAPA CCHHHHHCCCCCCCC	51.91	28555341
77	Phosphorylation	AQPRPLRSLSPSVRQ CCCCCCCCCCHHHHH	40.66	30266825
79	Phosphorylation	PRPLRSLSPSVRQLS CCCCCCCCHHHHHHH	19.17	30266825
81	Phosphorylation	PLRSLSPSVRQLSRR CCCCCCHHHHHHHHH	26.93	30266825
125	Phosphorylation	PARGAWPSVTEMRKL CCCCCCCCHHHHHHH	30.85	28857561
138	Phosphorylation	KLFGGPGSRRPSADS HHHCCCCCCCCCCCC	28.40	22817900
142	Phosphorylation	GPGSRRPSADSESPG CCCCCCCCCCCCCCC	42.78	23401153
145	Phosphorylation	SRRPSADSESPGTPS CCCCCCCCCCCCCCC	39.42	23927012
147	Phosphorylation	RPSADSESPGTPSPD CCCCCCCCCCCCCCC	32.36	23927012
150	Phosphorylation	ADSESPGTPSPDGAA CCCCCCCCCCCCCCC	24.79	23927012
152	Phosphorylation	SESPGTPSPDGAAWE CCCCCCCCCCCCCCC	35.15	23403867
170	Phosphorylation	RESRQPPTPPPRTCF CCCCCCCCCCCCCCC	55.93	30266825
175	Phosphorylation	PPTPPPRTCFPLAGL CCCCCCCCCCCCCCC	25.03	24043423
189	Phosphorylation	LRSARPLTGPETEGR CCCCCCCCCCCCCCC	54.06	28634298
193	Phosphorylation	RPLTGPETEGRLRRP CCCCCCCCCCCCCCH	47.04	28634298
216	Phosphorylation	RPADGLHSWHIFSQP CCCCCCCCEEEECCC	25.95	28555341
230	Phosphorylation	PQAGARASCSSSSIA CCCCCCCCCCCCHHH	14.69	28857561
232	Phosphorylation	AGARASCSSSSIAAS CCCCCCCCCCHHHHC	30.66	28857561
233	Phosphorylation	GARASCSSSSIAASY CCCCCCCCCHHHHCC	32.22	28857561
234	Phosphorylation	ARASCSSSSIAASYP CCCCCCCCHHHHCCC	14.96	28857561
235	Phosphorylation	RASCSSSSIAASYPV CCCCCCCHHHHCCCC	20.42	28857561
239	Phosphorylation	SSSSIAASYPVSRSR CCCHHHHCCCCCHHH	22.43	28102081
243	Phosphorylation	IAASYPVSRSRAASS HHHCCCCCHHHCCCC	21.75	28102081
245	Phosphorylation	ASYPVSRSRAASSSE HCCCCCHHHCCCCCC	20.82	28102081
310	Phosphorylation	DQDCRPDSDGLNLSS CCCCCCCCCCCCHHH	35.94	26471730
316	Phosphorylation	DSDGLNLSSMNSAGV CCCCCCHHHCCCCCC	26.85	28348404
317	Phosphorylation	SDGLNLSSMNSAGVS CCCCCHHHCCCCCCC	25.75	28348404
320	Phosphorylation	LNLSSMNSAGVSGSP CCHHHCCCCCCCCCC	20.12	28348404
324	Phosphorylation	SMNSAGVSGSPEPPT HCCCCCCCCCCCCCC	32.41	26471730
326	Phosphorylation	NSAGVSGSPEPPTSP CCCCCCCCCCCCCCC	20.70	26471730
331	Phosphorylation	SGSPEPPTSPRAPRE CCCCCCCCCCCCCHH	63.18	26471730
332	Phosphorylation	GSPEPPTSPRAPREE CCCCCCCCCCCCHHH	20.40	26471730
346	Phosphorylation	EGLREWGSGSPPCVP HCHHHCCCCCCCCCC	36.85	22210691
348	Phosphorylation	LREWGSGSPPCVPGP HHHCCCCCCCCCCCC	27.63	28857561
376	Phosphorylation	AFRVAKVSFPSYLAS CEEEEEECCCHHHCC	30.63	26657352
379	Phosphorylation	VAKVSFPSYLASPAG EEEECCCHHHCCCCC	30.67	30266825
380	Phosphorylation	AKVSFPSYLASPAGS EEECCCHHHCCCCCC	13.41	23403867
383	Phosphorylation	SFPSYLASPAGSRGS CCCHHHCCCCCCCCC	16.82	30266825
387	Phosphorylation	YLASPAGSRGSSRYS HHCCCCCCCCCCCCC	35.26	30266825
390	Phosphorylation	SPAGSRGSSRYSSTE CCCCCCCCCCCCCCC	15.55	29978859
391	Phosphorylation	PAGSRGSSRYSSTET CCCCCCCCCCCCCCC	37.75	29978859
393	Phosphorylation	GSRGSSRYSSTETLK CCCCCCCCCCCCCCC	14.66	23403867
394	Phosphorylation	SRGSSRYSSTETLKD CCCCCCCCCCCCCCC	29.67	23927012
395	Phosphorylation	RGSSRYSSTETLKDD CCCCCCCCCCCCCCC	22.71	27273156
396	Phosphorylation	GSSRYSSTETLKDDD CCCCCCCCCCCCCCC	27.35	26657352
398	Phosphorylation	SRYSSTETLKDDDLW CCCCCCCCCCCCCCC	38.91	23403867
406	Phosphorylation	LKDDDLWSSRGSGGW CCCCCCCCCCCCCCC	19.91	23403867
407	Phosphorylation	KDDDLWSSRGSGGWG CCCCCCCCCCCCCCC	29.13	23403867
410	Phosphorylation	DLWSSRGSGGWGVYR CCCCCCCCCCCCCCC	32.78	25159151
416	Phosphorylation	GSGGWGVYRSPSFGA CCCCCCCCCCCCCCC	11.05	27642862
418	Phosphorylation	GGWGVYRSPSFGAGE CCCCCCCCCCCCCCC	13.75	27273156
420	Phosphorylation	WGVYRSPSFGAGEGL CCCCCCCCCCCCCCH	37.24	23401153
429	Methylation	GAGEGLLRSQARTRA CCCCCHHHHHHCHHC	31.59	-
433	Methylation	GLLRSQARTRAKGPG CHHHHHHCHHCCCCC	19.67	-
461	Phosphorylation	EKSRQRKSLSNPDIA HHHHCCHHCCCHHHH	38.94	26846344
463	Phosphorylation	SRQRKSLSNPDIASE HHCCHHCCCHHHHHH	54.10	26846344
469	Phosphorylation	LSNPDIASETLTLLS CCCHHHHHHHHHHHH	31.29	29632367
471	Phosphorylation	NPDIASETLTLLSFL CHHHHHHHHHHHHHH	23.65	29496963
473	Phosphorylation	DIASETLTLLSFLRS HHHHHHHHHHHHHHC	32.83	26846344
476	Phosphorylation	SETLTLLSFLRSDLS HHHHHHHHHHHCCHH	25.91	26846344
499	Phosphorylation	GSSGDRGSNPLDGRD CCCCCCCCCCCCCCC	35.85	30266825
507	Phosphorylation	NPLDGRDSPSAGGPV CCCCCCCCCCCCCCC	21.28	30266825
509	Phosphorylation	LDGRDSPSAGGPVGQ CCCCCCCCCCCCCCC	43.42	23401153
527	Phosphorylation	IPIPAPASPGTRPTL CCCCCCCCCCCCCCH	23.85	29255136
530	Phosphorylation	PAPASPGTRPTLKDL CCCCCCCCCCCHHHH	36.54	29255136
533	Phosphorylation	ASPGTRPTLKDLTAT CCCCCCCCHHHHHHH	43.05	29255136
535	Acetylation	PGTRPTLKDLTATLR CCCCCCHHHHHHHHH	53.85	15614345
546	Phosphorylation	ATLRRAKSFTCSEKP HHHHHHHHCCCCCCH	25.46	23927012
548	Phosphorylation	LRRAKSFTCSEKPMA HHHHHHCCCCCCHHH	23.39	23927012
550	Phosphorylation	RAKSFTCSEKPMARR HHHHCCCCCCHHHHC	45.67	23403867
566	Phosphorylation	PRTSALKSSSSELLL CCCHHHCCCCCCEEE	35.98	27251789
567	Phosphorylation	RTSALKSSSSELLLT CCHHHCCCCCCEEEC	35.97	26657352
568	Phosphorylation	TSALKSSSSELLLTG CHHHCCCCCCEEECC	34.62	28857561
569	Phosphorylation	SALKSSSSELLLTGP HHHCCCCCCEEECCC	33.92	26657352
574	Phosphorylation	SSSELLLTGPGAEED CCCCEEECCCCCCCC	41.10	29116813
601	Ubiquitination	EARQVFEKIQRMGAQ HHHHHHHHHHHHCCC	32.45	29967540
613	Phosphorylation	GAQQDDGSDAPPGSP CCCCCCCCCCCCCCC	37.28	23403867
619	Phosphorylation	GSDAPPGSPDWAGDV CCCCCCCCCCCHHCC	26.01	28355574
627	Phosphorylation	PDWAGDVTRGQRSQE CCCHHCCCCCCCCHH	33.55	23403867
696	Phosphorylation	LGGWALVSPETPPTP CCCEEEECCCCCCCC	20.19	24719451
699	Phosphorylation	WALVSPETPPTPGAL EEEECCCCCCCCCHH	37.64	25850435
702	Phosphorylation	VSPETPPTPGALRRR ECCCCCCCCCHHHCC	35.24	24719451
720	Phosphorylation	PPSGSGGSELSNGEA CCCCCCCCCCCCCCC	38.60	25627689
723	Phosphorylation	GSGGSELSNGEAGEA CCCCCCCCCCCCHHH	38.44	25627689
733	Phosphorylation	EAGEAYRSLSDPIPQ CCHHHHHHCCCCCCH	21.39	30266825
735	Phosphorylation	GEAYRSLSDPIPQRH HHHHHHCCCCCCHHH	42.46	30266825
746	Phosphorylation	PQRHRAATSEEPTGF CHHHCCCCCCCCCCC	35.37	23403867
747	Phosphorylation	QRHRAATSEEPTGFS HHHCCCCCCCCCCCC	34.92	23403867
751	Phosphorylation	AATSEEPTGFSVDSN CCCCCCCCCCCCCHH	54.89	-
754	Phosphorylation	SEEPTGFSVDSNLLG CCCCCCCCCCHHHHC	26.76	30266825
757	Phosphorylation	PTGFSVDSNLLGSLS CCCCCCCHHHHCCCC	27.50	30266825
762	Phosphorylation	VDSNLLGSLSPKTGL CCHHHHCCCCCCCCC	26.16	30266825
764	Phosphorylation	SNLLGSLSPKTGLPA HHHHCCCCCCCCCCC	26.50	30266825
780	Phosphorylation	SAMDEGLTSGHSDWS HHHCCCCCCCCCCCC	43.44	27251275
781	Phosphorylation	AMDEGLTSGHSDWSV HHCCCCCCCCCCCCC	39.28	27251275
784	Phosphorylation	EGLTSGHSDWSVGSE CCCCCCCCCCCCCCH	44.28	27251275
787	Phosphorylation	TSGHSDWSVGSEESK CCCCCCCCCCCHHCC	22.91	22777824
790	Phosphorylation	HSDWSVGSEESKGYQ CCCCCCCCHHCCCHH	35.71	22777824
793	Phosphorylation	WSVGSEESKGYQEVI CCCCCHHCCCHHHHH	27.59	27251275
796	Phosphorylation	GSEESKGYQEVIQSI CCHHCCCHHHHHHHH	12.77	27642862
802	Phosphorylation	GYQEVIQSIVQGPGT CHHHHHHHHHCCCCH	17.38	26503514
809	Phosphorylation	SIVQGPGTLGRVVDD HHHCCCCHHHHHCCH	29.22	26503514
827	Phosphorylation	GKAPKKKSLSDPSRR CCCCCCCCCCCHHHC	41.82	23927012
829	Phosphorylation	APKKKSLSDPSRRGE CCCCCCCCCHHHCCC	55.34	29255136
832	Phosphorylation	KKSLSDPSRRGELAG CCCCCCHHHCCCCCC	39.33	23927012
860	Phosphorylation	VEPMLPPSSSEPILV CCCCCCCCCCCCEEE	44.55	26657352
861	Phosphorylation	EPMLPPSSSEPILVE CCCCCCCCCCCEEEE	44.48	26657352
862	Phosphorylation	PMLPPSSSEPILVEQ CCCCCCCCCCEEEEE	52.29	26657352
881	Phosphorylation	EEPGATRSRAQSERA CCCCCCHHHHHHHHC	27.84	24719451
885	Phosphorylation	ATRSRAQSERALPEA CCHHHHHHHHCCCCC	28.23	-
898	Phosphorylation	EALPPPATAHRNFHL CCCCCCCHHHCCCCC	28.86	-
914	Phosphorylation	PKLADILSPRLIRRG HHHHHHHCHHHHHCC	14.33	30266825
929	Phosphorylation	SKKRPARSSHQELRR CCCCCCCHHCHHHHH	33.99	26074081
930	Phosphorylation	KKRPARSSHQELRRD CCCCCCHHCHHHHHC	24.52	26074081
940	Phosphorylation	ELRRDEGSQDQTGSL HHHHCCCCCCCCCCC	28.65	24719451
944	Phosphorylation	DEGSQDQTGSLSRAR CCCCCCCCCCCCCCC	36.71	29255136
946	Phosphorylation	GSQDQTGSLSRARPS CCCCCCCCCCCCCCC	26.93	29255136
948	Phosphorylation	QDQTGSLSRARPSSR CCCCCCCCCCCCCCC	26.12	29255136
961	Phosphorylation	SRHVRHASVPATFMP CCCCCCCCCCCEECC	23.62	29255136
965	Phosphorylation	RHASVPATFMPIVVP CCCCCCCEECCEECC	17.88	29255136
976	Phosphorylation	IVVPEPPTSVGPPVA EECCCCCCCCCCCCC	46.92	28857561
977	Phosphorylation	VVPEPPTSVGPPVAV ECCCCCCCCCCCCCC	30.74	28857561
1002	Phosphorylation	HPTLQAPSLEDVTKQ CCCCCCCCHHHHHHH	47.62	29255136
1007	Phosphorylation	APSLEDVTKQYMLNL CCCHHHHHHHHHHHC	25.42	23403867
1073	Phosphorylation	MRKHVAMTLLDTEQS HHHHHHHHHHHHHHH	17.90	28270605
1077	Phosphorylation	VAMTLLDTEQSYVES HHHHHHHHHHHHHHH	35.57	28270605
1080	Phosphorylation	TLLDTEQSYVESLRT HHHHHHHHHHHHHHH	25.55	24719451
1081	Phosphorylation	LLDTEQSYVESLRTL HHHHHHHHHHHHHHH	14.13	22210691
1084	Phosphorylation	TEQSYVESLRTLMQG HHHHHHHHHHHHHHH	17.07	28270605
1087	Phosphorylation	SYVESLRTLMQGYMQ HHHHHHHHHHHHHCC	31.69	22210691
1151	Phosphorylation	VGALLVQSFSKDVLV HHHHHHHCCCHHHHH	24.82	24719451
1192	Phosphorylation	FLKFLEQSMRENKEK HHHHHHHHHHHCHHH	15.49	24670416
1245	Ubiquitination	LEAQRNIKQVAERIN HHHHHHHHHHHHHHH	42.12	29967540
1257	Phosphorylation	RINKGVRSAEEAERH HHHHHHCCHHHHHHH	37.31	28122231
1330	Phosphorylation	KSGSLRRSSMSLYTA CCCCCCCCHHHHHHH	24.78	26657352
1331	Phosphorylation	SGSLRRSSMSLYTAA CCCCCCCHHHHHHHH	15.58	21712546
1333	Phosphorylation	SLRRSSMSLYTAASV CCCCCHHHHHHHHHH	21.85	26657352
1335	Phosphorylation	RRSSMSLYTAASVID CCCHHHHHHHHHHHH	6.24	23403867
1336	Phosphorylation	RSSMSLYTAASVIDT CCHHHHHHHHHHHHH	22.50	23403867
1339	Phosphorylation	MSLYTAASVIDTASK HHHHHHHHHHHHHHH	19.69	23403867
1343	Phosphorylation	TAASVIDTASKYKML HHHHHHHHHHHHCEE	23.00	23403867
1345	Phosphorylation	ASVIDTASKYKMLWK HHHHHHHHHHCEEEC	38.31	23403867
1347	Phosphorylation	VIDTASKYKMLWKLP HHHHHHHHCEEECCC	10.11	22210691
1385	Phosphorylation	SRLDEDLTTLGQMSK HHHHHHHHHHHHHHH	32.09	-
1430	Phosphorylation	QALCYALSFPPTKLE HHHHHHHCCCCCEEE	27.77	-
1470	Ubiquitination	EQAFDEAKRKLASSK HHHHHHHHHHHHCCC	48.28	29967540
1478	Phosphorylation	RKLASSKSCLDPEFL HHHHCCCHHCCHHHH	23.12	27251275
1513	Phosphorylation	LNSCPEPSPEVWVCN CCCCCCCCCCEEEEC	31.84	-
1521	Phosphorylation	PEVWVCNSDGYVGQV CCEEEECCCCCCEEE	27.56	-
1661	Phosphorylation	QASRSTISSSFGNEE HHHHHHHHHHCCCCC	21.73	28857561
1662	Phosphorylation	ASRSTISSSFGNEET HHHHHHHHHCCCCCC	26.32	24719451
1663	Phosphorylation	SRSTISSSFGNEETP HHHHHHHHCCCCCCC	30.31	28857561
1669	Phosphorylation	SSFGNEETPSSKEAT HHCCCCCCCCCCCCC	23.45	21815630
1671	Phosphorylation	FGNEETPSSKEATAE CCCCCCCCCCCCCCC	62.55	27732954
1672	Phosphorylation	GNEETPSSKEATAET CCCCCCCCCCCCCCC	35.40	27732954
1705	Phosphorylation	GPGGPCGTSPMDGRA CCCCCCCCCCCCCCC	36.05	28348404
1706	Phosphorylation	PGGPCGTSPMDGRAL CCCCCCCCCCCCCCH	11.96	28348404
1716	Phosphorylation	DGRALRRSSHGSFTR CCCCHHHCCCCCCCC	21.91	26699800
1717	Phosphorylation	GRALRRSSHGSFTRG CCCHHHCCCCCCCCC	30.01	30576142
1720	Phosphorylation	LRRSSHGSFTRGSLE HHHCCCCCCCCCCHH	20.30	30576142
1722	Phosphorylation	RSSHGSFTRGSLEDL HCCCCCCCCCCHHHH	35.50	27732954
1725	Phosphorylation	HGSFTRGSLEDLLSV CCCCCCCCHHHHHCC	25.87	24043423
1731	Phosphorylation	GSLEDLLSVDPEAYQ CCHHHHHCCCHHHHH	31.60	24043423
1737	Phosphorylation	LSVDPEAYQSSVWLG HCCCHHHHHCCEEEE	13.78	24043423
1739	Phosphorylation	VDPEAYQSSVWLGTE CCHHHHHCCEEEECC	17.74	24043423
1740	Phosphorylation	DPEAYQSSVWLGTED CHHHHHCCEEEECCC	11.20	24043423
1745	Phosphorylation	QSSVWLGTEDGCVHV HCCEEEECCCCCEEE	28.82	24043423
1753	Phosphorylation	EDGCVHVYQSSDSIR CCCCEEEEECCHHHH	6.44	24043423
1755	Phosphorylation	GCVHVYQSSDSIRDR CCEEEEECCHHHHHH	20.58	24043423
1756	Phosphorylation	CVHVYQSSDSIRDRR CEEEEECCHHHHHHH	21.61	24043423
1758	Phosphorylation	HVYQSSDSIRDRRNS EEEECCHHHHHHHHH	22.82	24043423
1811	Phosphorylation	WDPQNFKSVTLGTQG CCCCCCCEEEEECCC	19.05	-
1961	Phosphorylation	SCPRAPLSPTGLGQG ECCCCCCCCCCCCCC	21.25	29255136
1963	Phosphorylation	PRAPLSPTGLGQGHT CCCCCCCCCCCCCCC	41.48	28857561
1991	Phosphorylation	GFNLLCPTPPPPPDT CCCEECCCCCCCCCC	47.64	26657352
2005	Phosphorylation	TGPEKLPSLEHRDSP CCCCCCCCCCCCCCC	57.75	23312004
2011	Phosphorylation	PSLEHRDSPWHRGPA CCCCCCCCCCCCCCC	29.82	26270265
2055	Phosphorylation	TVGRDDSTNHLLLWR CCCCCCCCCCEEEEE	33.38	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
751	T	Phosphorylation	Kinase	TTK	P33981	PSP
944	T	Phosphorylation	Kinase	TTK	P33981	PSP
1007	T	Phosphorylation	Kinase	TTK	P33981	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ARHGH_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
379	Phosphorylation	388 (9)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
383	Phosphorylation	388 (5)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
387	Phosphorylation	388 (1)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
390	Phosphorylation	388 (2)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
391	Phosphorylation	388 (3)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
393	Phosphorylation	388 (5)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
394	Phosphorylation	388 (6)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
395	Phosphorylation	388 (7)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273
396	Phosphorylation	388 (8)	R ⇒ H;P;L	rs3741151	GIP levels in response to oral glucose tolerance test (120 minutes)	29093273

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ARHGH_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ARHGH_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-138, AND MASSSPECTROMETRY.	18187866 [Abstract]