dbPTM

PTEN_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PTEN_SCHPO
UniProt AC	O94526
Protein Name	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1
Gene Name	ptn1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	348
Subcellular Localization	Cytoplasmic vesicle .
Protein Description	Acts as a phosphoinositide 3-phosphatase and regulates PtdIns(3,4,5)P3 levels..
Protein Sequence	MNILRSVVSRGRKGLKQEKVNRSFAYLDMVYITSKVIAMSTPAAGIHKLYRNDELDVFKYLTTQLKDNWILLNLCAEETVYHLELFKPNVINYGFQDHNPPPLLFLWAIVMNMDALFQTQPLLTLVVHCKAGKGRTGTVICSYLVAFGGLTAKQSLELYTEKRMVRGHGLTISSQIRYVYYIEILKQFPNYLKAVEFNTGTTFFKSFKCLNIKKNSSLILSLHAFSKGRNINPVALWKSSDISSHNVSIKEGKRIWGIQCNLETSEKDLLLRVERKGQFYFPSSVQCWFHTHFQPMLVEYTNGINFQQGINSFLQGQQSISFSWSEMDNSRRSDPFFEQLTIVYENVF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of PTEN_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PTEN_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PTEN_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PTEN_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SNF8_SCHPO	dot2	genetic	18818364
UBP3_SCHPO	ubp3	genetic	18818364
RPA12_SCHPO	rpa12	genetic	18818364
DCR1_SCHPO	dcr1	genetic	18818364
CDS1_SCHPO	cds1	genetic	18818364
SPP1_SCHPO	spf1	genetic	18818364
GNR1_SCHPO	gnr1	genetic	18818364
VPS34_SCHPO	pik3	genetic	15249580
IMB5_SCHPO	kap114	genetic	22681890
PRZ1_SCHPO	prz1	genetic	22681890
MCL1_SCHPO	mcl1	genetic	22681890

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PTEN_SCHPO

Related Literatures of Post-Translational Modification