dbPTM

PLPHP_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PLPHP_SCHPO
UniProt AC	Q9P6Q1
Protein Name	Pyridoxal phosphate homeostasis protein {ECO:0000255\|HAMAP-Rule:MF_03225}
Gene Name	SPAC644.09
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	237
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6..
Protein Sequence	MSTIHSCLDLIRSQIQQSANGRNVLLVAVSKFHPVETLMEAYNAGQRHFGENYMQEFLKKVELMPDDVQWHFIGSLQSSKCKKIASVKNLYSIETIDTEKKARLVNSAREALQLPLNVYIQVNTSGEENKGGVTPSKVLELCKQVQDMKYLRLKGLMTIGSISNSQLSDHNPDFQVLSDLRESLQNELGIPLQLSMGMSSDYLLAIKYGSDSVRVGSSIFGSRPTEKPSDVHISASK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
31	N6-(pyridoxal phosphate)lysine	VLLVAVSKFHPVETL EEEEEEEECCCHHHH		-
31	Other	VLLVAVSKFHPVETL EEEEEEEECCCHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PLPHP_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PLPHP_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PLPHP_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YB3C_SCHPO	cay1	genetic	18818364
VTA1_SCHPO	vta1	genetic	22681890
EIF2A_SCHPO	SPBC4B4.04	genetic	22681890
PROB_SCHPO	SPAC17H9.13c	genetic	22681890
PDX1_SCHPO	snz1	genetic	22681890
PAM17_SCHPO	pam17	genetic	22681890
ULP2_SCHPO	ulp2	genetic	22681890
AATC_SCHPO	SPAC10F6.13c	genetic	22681890
YE08_SCHPO	SPAC17H9.08	genetic	22681890
PAB2_SCHPO	pab2	genetic	22681890
SSN3_SCHPO	srb10	genetic	22681890
YFM8_SCHPO	SPAC222.08c	genetic	22681890
ELOF1_SCHPO	SPAC1B3.02c	genetic	22681890

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PLPHP_SCHPO

Related Literatures of Post-Translational Modification