| UniProt ID | PKHB1_MOUSE | |
|---|---|---|
| UniProt AC | Q9QYE9 | |
| Protein Name | Pleckstrin homology domain-containing family B member 1 | |
| Gene Name | Plekhb1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 243 | |
| Subcellular Localization | Membrane . Cytoplasm . Membrane-associated. Highly expressed in the outer segments of photoreceptor cells, both in rods and cones (By similarity). Localizes to the apical juxta-nuclear Golgi region of the cytoplasm (PubMed:20301200). | |
| Protein Description | ||
| Protein Sequence | MSPATPVPPDSILESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVVIHFNVRDIKVGQECQDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALMEANSTPAPAGATVPPRSRRVCPKVRCTTLSWNPCKVERRIWVRVYSPYQDYYEVVPPNAHEATYVRSYYGPPYAGPGVTHVIVREDPCYSSGAPLAMGMLAGAATGAALGSLMWSPCWF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 76 | Ubiquitination | HFNVRDIKVGQECQD EEEECEEECCCCCCC | 44.60 | - | |
| 169 | Phosphorylation | RRIWVRVYSPYQDYY EEEEEEEECCCCCEE | 8.05 | - | |
| 172 | Phosphorylation | WVRVYSPYQDYYEVV EEEEECCCCCEEECC | 14.21 | - | |
| 175 | Phosphorylation | VYSPYQDYYEVVPPN EECCCCCEEECCCCC | 5.99 | 22817900 | |
| 176 | Phosphorylation | YSPYQDYYEVVPPNA ECCCCCEEECCCCCC | 15.55 | 22817900 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PKHB1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PKHB1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PKHB1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MYO1C_MOUSE | Myo1c | physical | 15976448 | |
| MYO7A_MOUSE | Myo7a | physical | 15976448 | |
| PKHB1_MOUSE | Plekhb1 | physical | 15976448 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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