dbPTM

P2C25_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	P2C25_ARATH
UniProt AC	O80871
Protein Name	Probable protein phosphatase 2C 25
Gene Name	At2g30020
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	396
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Protein phosphatase that negatively regulates defense respones. Inactivates MPK4 and MPK6 MAP kinases involved in stress and defense signaling..
Protein Sequence	MSCSVAVCNSPVFSPSSSLFCNKSSILSSPQESLSLTLSHRKPQTSSPSSPSTTVSSPKSPFRLRFQKPPSGFAPGPLSFGSESVSASSPPGGVLKRKRPTRLDIPIGVAGFVAPISSSAAVAATPREECREVEREGDGYSVYCKRGRREAMEDRFSAITNLHGDRKQAIFGVYDGHGGVKAAEFAAKNLDKNIVEEVVGKRDESEIAEAVKHGYLATDASFLKEEDVKGGSCCVTALVNEGNLVVSNAGDCRAVMSVGGVAKALSSDHRPSRDDERKRIETTGGYVDTFHGVWRIQGSLAVSRGIGDAQLKKWVIAEPETKISRIEHDHEFLILASDGLWDKVSNQEAVDIARPLCLGTEKPLLLAACKKLVDLSASRGSSDDISVMLIPLRQFI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of P2C25_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of P2C25_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of P2C25_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of P2C25_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MPK4_ARATH	MPK4	physical	24908126
MPK6_ARATH	MPK6	physical	24908126
PYR1_ARATH	PYR1	physical	24833385
OST48_ARATH	DGL1	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
POT10_ARATH	KUP10	physical	24833385
WTR25_ARATH	AT3G45870	physical	24833385
MPK6_ARATH	MPK6	physical	17630279
MPK4_ARATH	MPK4	physical	17630279

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of P2C25_ARATH

Related Literatures of Post-Translational Modification