dbPTM

P24DA_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	P24DA_ARATH
UniProt AC	Q8VY92
Protein Name	Transmembrane emp24 domain-containing protein p24delta10
Gene Name	At1g69460
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	214
Subcellular Localization	Endoplasmic reticulum membrane Single-pass type I membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane Single-pass type I membrane protein . Golgi apparatus, cis-Golgi network membrane Single-pass type I membrane protein
Protein Description	Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side (By similarity)..
Protein Sequence	MFLQSQKLWTMLLILAIWSPISHSLHFDLHSGRTKCIAEDIKSNSMTVGKYNIDNPHEGQALPQTHKISVKVTSNSGNNYHHAEQVDSGQFAFSAVEAGDYMACFTAVDHKPEVSLSIDFEWKTGVQSKSWANVAKKSQVEVMEFEVKSLLDTVNSIHEEMYYLRDREEEMQDLNRSTNTKMAWLSVLSFFVCIGVAGMQFLHLKTFFEKKKVI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
167	Methylation	EMYYLRDREEEMQDL HHHHHHCHHHHHHHH		-
175	N-linked_Glycosylation	EEEMQDLNRSTNTKM HHHHHHHHHHHHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of P24DA_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of P24DA_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of P24DA_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PIP15_ARATH	PIP1;5	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
C71B4_ARATH	CYP71B4	physical	24833385
DERL1_ARATH	DER1	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
BET12_ARATH	ATBET12	physical	24833385

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of P24DA_ARATH

Related Literatures of Post-Translational Modification