OXI1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OXI1_ARATH
• UniProt AC: Q9LSF1
• Protein Name: Serine/threonine-protein kinase OXI1
• Gene Name: OXI1 {ECO:0000303|PubMed:14985766}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 421
• Protein Description: Involved in oxidative burst-mediated signaling. Required for basal resistance to P.parasitica infection and root hair growth. Partly required for the activation of MPK3 and MPK6 by hydrogen peroxide and cellulase elicitor..
• Protein Sequence: MLEGDEKQSRALDFNRLEVLSLLGRGAKGVVFLVRDDDAKLLALKVILKEAIEKKKKGRESEDDEYKRVSFEQGVLSRFDHPLFPSLHGVLATDKVIGYAIDYCPGQNLNSLRKMQSESMFSDEIIRFYAAELVLALDYLHNQGIVYRDLKPDNVMIQENGHLMLIDFDLSTNLAPRTPQPSPSLSKPSPTMKRKKRLFRFTSFCNSGISPQESISVHSSSTLAVSDSSGEKSNSFVGTEEYVAPEVISGDGHDFAVDWWSLGVVLYEMLYGATPFRGSNRKETFYRILSKPPNLTGETTSLRDLIRRLLEKDPSRRINVEEIKGHDFFRGVDWEKVILVSRPPYIPAPDDGGDKGTDVNTKMDVENIVQEIFAARQEREKQSGDNNKNANMKIKDNTSGEWVKGLNNNHDLESDNNFLVF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
235	Phosphorylation	SSGEKSNSFVGTEEY CCCCCCCCCCCCCEE	28.53	-
300	Phosphorylation	PNLTGETTSLRDLIR CCCCCCCCCHHHHHH	22.82	24894044
301	Phosphorylation	NLTGETTSLRDLIRR CCCCCCCCHHHHHHH	28.91	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
235	S	Phosphorylation	Kinase	PDPK1	Q9XF67	Uniprot

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OXI1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OXI1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PTI11_ARATH	AT1G06700	physical	17040918
PTI12_ARATH	AT2G30740	physical	17040918
PTI13_ARATH	AT3G59350	physical	17040918
PDPK1_ARATH	PDK1	physical	14749726
Y2706_ARATH	AT2G47060	physical	21276203

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.