OSER1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OSER1_HUMAN
• UniProt AC: Q9NX31
• Protein Name: Oxidative stress-responsive serine-rich protein 1
• Gene Name: OSER1
• Organism: Homo sapiens (Human).
• Sequence Length: 292
• Protein Sequence: MKSEAKDGEEESLQTAFKKLRVDASGSVASLSVGEGTGVRAPVRTATDDTKPKTTCASKDSWHGSTRKSSRGAVRTQRRRRSKSPVLHPPKFIHCSTIASSSSSQLKHKSQTDSPDGSSGLGISSPKEFSAGESSTSLDANHTGAVVEPLRTSVPRLPSESKKEDSSDATQVPQASLKASDLSDFQSVSKLNQGKPCTCIGKECQCKRWHDMEVYSFSGLQSVPPLAPERRSTLEDYSQSLHARTLSGSPRSCSEQARVFVDDVTIEDLSGYMEYYLYIPKKMSHMAEMMYT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Methylation	SLQTAFKKLRVDASG HHHHHHHHHCCCCCC		115974483
25	Phosphorylation	KKLRVDASGSVASLS HHHCCCCCCCEEEEE		22817900
32	Phosphorylation	SGSVASLSVGEGTGV CCCEEEEEECCCCCE		22964224
37	Phosphorylation	SLSVGEGTGVRAPVR EEEECCCCCEECCEE		22964224
45	Phosphorylation	GVRAPVRTATDDTKP CEECCEECCCCCCCC		22817900
47	Phosphorylation	RAPVRTATDDTKPKT ECCEECCCCCCCCCC		22817900
50	Phosphorylation	VRTATDDTKPKTTCA EECCCCCCCCCCCCC		22817900
53	Ubiquitination	ATDDTKPKTTCASKD CCCCCCCCCCCCCCC		29967540
59	Ubiquitination	PKTTCASKDSWHGST CCCCCCCCCCCCCCC		29967540
69	Phosphorylation	WHGSTRKSSRGAVRT CCCCCCHHCCHHHHH		-
82	Phosphorylation	RTQRRRRSKSPVLHP HHHHHHHCCCCCCCC		22167270
84	Phosphorylation	QRRRRSKSPVLHPPK HHHHHCCCCCCCCCC		22167270
107	Ubiquitination	SSSSSQLKHKSQTDS CCCCHHHCCCCCCCC		29967540
109	Ubiquitination	SSSQLKHKSQTDSPD CCHHHCCCCCCCCCC		29967540
110	Phosphorylation	SSQLKHKSQTDSPDG CHHHCCCCCCCCCCC		23312004
112	Phosphorylation	QLKHKSQTDSPDGSS HHCCCCCCCCCCCCC		22199227
114	Phosphorylation	KHKSQTDSPDGSSGL CCCCCCCCCCCCCCC		21815630
118	Phosphorylation	QTDSPDGSSGLGISS CCCCCCCCCCCCCCC		22199227
119	Phosphorylation	TDSPDGSSGLGISSP CCCCCCCCCCCCCCC		22199227
124	Phosphorylation	GSSGLGISSPKEFSA CCCCCCCCCCCEECC		22199227
125	Phosphorylation	SSGLGISSPKEFSAG CCCCCCCCCCEECCC		21815630
127	Ubiquitination	GLGISSPKEFSAGES CCCCCCCCEECCCCC		29967540
137	Phosphorylation	SAGESSTSLDANHTG CCCCCCCCCCCCCCC		-
140	Ubiquitination	ESSTSLDANHTGAVV CCCCCCCCCCCCEEE		21963094
143	Phosphorylation	TSLDANHTGAVVEPL CCCCCCCCCEEEEEH		-
152	Ubiquitination	AVVEPLRTSVPRLPS EEEEEHHHCCCCCCC		21963094
157	Ubiquitination	LRTSVPRLPSESKKE HHHCCCCCCCCCCCC		21963094
159	Phosphorylation	TSVPRLPSESKKEDS HCCCCCCCCCCCCCC		29083192
161	Phosphorylation	VPRLPSESKKEDSSD CCCCCCCCCCCCCCC		29083192
163	Ubiquitination	RLPSESKKEDSSDAT CCCCCCCCCCCCCCC		29967540
164	Ubiquitination	LPSESKKEDSSDATQ CCCCCCCCCCCCCCC		21963094
166	Phosphorylation	SESKKEDSSDATQVP CCCCCCCCCCCCCCC		29083192
167	Phosphorylation	ESKKEDSSDATQVPQ CCCCCCCCCCCCCCH		29083192
169	Ubiquitination	KKEDSSDATQVPQAS CCCCCCCCCCCCHHH		22817900
176	Phosphorylation	ATQVPQASLKASDLS CCCCCHHHHCHHCHH		-
178	Ubiquitination	QVPQASLKASDLSDF CCCHHHHCHHCHHHH		21963094
190	Ubiquitination	SDFQSVSKLNQGKPC HHHHHHHHHCCCCCC		27667366
195	Ubiquitination	VSKLNQGKPCTCIGK HHHHCCCCCCEECCC		21963094
202	Ubiquitination	KPCTCIGKECQCKRW CCCEECCCCCCCCCC		21963094
207	Ubiquitination	IGKECQCKRWHDMEV CCCCCCCCCCCCCEE		22817900
215	Phosphorylation	RWHDMEVYSFSGLQS CCCCCEEEEEECCCC		27642862
232	Phosphorylation	PLAPERRSTLEDYSQ CCCCCHHHCHHHHHH		23186163
233	Phosphorylation	LAPERRSTLEDYSQS CCCCHHHCHHHHHHH		29978859
237	Phosphorylation	RRSTLEDYSQSLHAR HHHCHHHHHHHHHHH		23186163
247	Phosphorylation	SLHARTLSGSPRSCS HHHHHHCCCCCCCHH		23312004
249	Phosphorylation	HARTLSGSPRSCSEQ HHHHCCCCCCCHHHH		28985074
275	Phosphorylation	DLSGYMEYYLYIPKK HHCCCEEEEEECHHH		-
276	Phosphorylation	LSGYMEYYLYIPKKM HCCCEEEEEECHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OSER1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OSER1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OSER1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LACC1_HUMAN	LACC1	physical	28514442
TSR3_HUMAN	TSR3	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.