OCH1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: OCH1_SCHPO
• UniProt AC: Q9UTR6
• Protein Name: Initiation-specific alpha-1,6-mannosyltransferase
• Gene Name: och1 {ECO:0000303|PubMed:11231017}
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 396
• Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus membrane ; Single-pass type II membrane protein . Is recycled between the trans-Golgi network and a late compartment of the endoplasmic reticulum.
• Protein Description: Mannosyltransferase involved in outer chain elongation of asparagine-linked oligosaccharides of the type Man(9)GlcNAc(2). May otherwise add the first alpha-1,6-mannose to the Man(8)GlNAc(2) core oligosaccharide from the ER. Represents the first enzymatic event required for synthesis of outer chain mannose linkages on yeast secretory proteins..
• Protein Sequence: MLRLRLRSIVIGAAIAGSILLLFNHGSIEGMEDLTEISMLEDYTPEAANKDYVGQQEEEELLYDQPSYIEEEEDPDLEAYLSDLEREELEHSLEELDEENNYKLHLRYSFSQLQDFDEENEAVHMIVPKDTYEFEVPYHADIPKLIWQTSKDPFDREVMKYTRFWRINHPSYSHAVLDDEQSKALVISSFGDSSVSKISQAYAMMPLPVLKADFFRYLVLLAKGGIYSDIDTAPLKHINNWIPREYRKRNIRLIVGIEADPDRPDWNDYYARRVQFCQWTIAAAPGHPILWELVRRITDETWKLHDSKKLSKNGESVMEWTGPGIWTDAIMDYLNWQYGPFSVENITNLEEPYLVGDVLILPITAFSPGVGHMGSKSPNDPMAYVQHFFAGSWKDD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
345	N-linked_Glycosylation	YGPFSVENITNLEEP CCCCCCCCCCCCCCC	44.20	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of OCH1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of OCH1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of OCH1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ALG3_SCHPO	alg3	genetic	20854854
OCH1_SCHPO	och1	physical	26771498
RRN11_SCHPO	rrn11	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.