| UniProt ID | NU131_SCHPO | |
|---|---|---|
| UniProt AC | Q9P797 | |
| Protein Name | Nucleoporin nup131 | |
| Gene Name | nup131 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 1142 | |
| Subcellular Localization | Nucleus . Nuclear rim. | |
| Protein Description | Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.. | |
| Protein Sequence | MFIVHRRFFQNEKAFTPAGKHEKVADGNKHETLATSEYPKVCASNDLYKILQISAPKVGNFTIHDAPVVGLIDSILEYYLYISVKVRKAWIAGYGSQPQNLICFDWERFTGILDQQSLNSPPLAGFVKPDPTSAEPGFLLLWPASGDLFYWERTSLMNVEVSAPEFPGFLHYRIQLKRYESCKNLVSAEPAGFFLTLSSGRLLHLNLKDSDGNSSIQVRILFPGLHIPNCLLSLYNSIFAFTSGRVIPIRCGSIKGPGERLVYSMHSGSTLRIWEIFGTGDHHLLRGFDIYDIILDSIQESFSYVNRFLILDFSVSTSDPYTLACLVSWRDNASLFNYAAIIISFNHQMIPHVSQFCHVRSYLSAILPSVCRIFLPSPGTVVFCVFDVTFAMFHKVRGKEGTFYVEENLVVNNLTSKSRVLDFGMEDAIYEKSTHTLLKTPALILLTEGHGIIRIESSASYLKTSFSATTYLRSRLSQFASQSPLFREQFLLNFDFTYNLSESEVYNTVFNLCDELYTTPCKKNMSVLETLHSQQRDLMEIVLVAFKYLHLSPSNRLQLWLKVAYCSALADLYELLMCNEKMSNLLRRVLKIMSSNDNIDELFLKKCLNINLLLQHLSSEYSQISGQDASNAQKRIEVIVNVNNVYGTIFGNELAYRQEKISKFTDPSSVIRSDLWTVEVDHLDLLRKQIEDSISLHRDVRDSKDAHILKVSNKLRKQILHLVEQNCLLIFDLHNGTDDTIVKSHNFQKFEEEFGNSRKEWLQYLASVGYLEKAIDLAEKVKDFQTMVILLDCLDPKDPTIKLQKQKACLNKYKEEFADVIFFYLVDTEQYASLLHDFLEYQSLLISFFEANDLLNLLWIFEAQNGNYGRASEILFRDCEPEENRIIGKISQLALAKLYSWTNRIEGENIILSNETEVIENHLAILLIQEQYAEMLSSLVDITEDEGEAVEAIVTSNCVNLSENSIRAWLVSSAVERLIQNEYTTLCEMVDFFSSFSLRECSFKEVDLALELLERATITKDVYFYLKDLVYRRFLLQVNWAEIIDAHEDLESSFFPMVKEIMLESDFLIWLQHMEHNIHDESKHYLKSEKNFLQSVYSSLSESQVEDYQMELFREKQIFSVLCKDRELYILIPKLLDVATKQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 767 | Phosphorylation | EWLQYLASVGYLEKA HHHHHHHHHCHHHHH | 17.30 | 24763107 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NU131_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NU131_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NU131_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RPA12_SCHPO | rpa12 | genetic | 18818364 | |
| RYH1_SCHPO | ryh1 | genetic | 22681890 | |
| YF48_SCHPO | SPAC3H5.08c | genetic | 22681890 | |
| JHD1_SCHPO | epe1 | genetic | 22681890 | |
| MTG1_SCHPO | mtg1 | genetic | 22681890 | |
| YQMA_SCHPO | SPCP1E11.10 | genetic | 22681890 | |
| EMC1_SCHPO | emc1 | genetic | 22681890 | |
| NU132_SCHPO | nup132 | genetic | 24637836 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
