dbPTM

NTF4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NTF4_HUMAN
UniProt AC	P34130
Protein Name	Neurotrophin-4
Gene Name	NTF4
Organism	Homo sapiens (Human).
Sequence Length	210
Subcellular Localization	Secreted.
Protein Description	Target-derived survival factor for peripheral sensory sympathetic neurons..
Protein Sequence	MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MLPLPSCSLPILLLF CCCCCCCCHHHHHHH	41.33	-
43	Phosphorylation	APEWDLLSPRVVLSR CCCHHHCCCEEEECC	20.25	24719451
76	N-linked_Glycosylation	ESAGAPANRSRRGVS HHCCCCCCCCCCCCC	41.21	UniProtKB CARBOHYD
83	Phosphorylation	NRSRRGVSETAPASR CCCCCCCCCCCCCHH	31.86	28348404
85	Phosphorylation	SRRGVSETAPASRRG CCCCCCCCCCCHHCC	30.36	24247654
109	Phosphorylation	GWVTDRRTAVDLRGR CEECCCCEEEECCCC	31.74	24702127

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NTF4_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NTF4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NTF4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NTRK2_HUMAN	NTRK2	physical	11855816
NTRK2_HUMAN	NTRK2	physical	11738045
ATL4_HUMAN	ADAMTSL4	physical	25416956
TRI68_HUMAN	TRIM68	physical	26186194
TRI68_HUMAN	TRIM68	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NTF4_HUMAN

Related Literatures of Post-Translational Modification