NSG2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NSG2_HUMAN
• UniProt AC: Q9Y328
• Protein Name: Neuronal vesicle trafficking-associated protein 2 {ECO:0000312|HGNC:HGNC:24955}
• Gene Name: NSG2 {ECO:0000312|HGNC:HGNC:24955}
• Organism: Homo sapiens (Human).
• Sequence Length: 171
• Subcellular Localization: Membrane ; Single-pass type II membrane protein . Golgi apparatus, trans-Golgi network membrane . Cell projection, dendrite . Endosome membrane . Early endosome membrane . Late endosome membrane . Lysosome lumen . Cytoplasmic vesicle membrane . Golgi appa
• Protein Sequence: MVKLNSNPSEKGTKPPSVEDGFQTVPLITPLEVNHLQLPAPEKVIVKTRTEYQPEQKNKGKFRVPKIAEFTVTILVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYKHKRCIPASLDAYYSSQDPNSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKTQGH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	Phosphorylation	FQTVPLITPLEVNHL CCCCCEECCEEECCC	29.51	-
52	Phosphorylation	IVKTRTEYQPEQKNK EEEECCCCCHHHCCC	28.84	25884760
57	Ubiquitination	TEYQPEQKNKGKFRV CCCCHHHCCCCCCCC	59.99	32142685
59	Ubiquitination	YQPEQKNKGKFRVPK CCHHHCCCCCCCCCH	71.20	30230243
116	Phosphorylation	HKRCIPASLDAYYSS CCCEEEHHHHHHHCC	22.79	-
133	Phosphorylation	PNSRSRFYTVISHYS CCCCHHHEEECCHHH	10.05	22461510
139	Phosphorylation	FYTVISHYSVAKQST HEEECCHHHHHCHHH	9.69	22461510
140	Phosphorylation	YTVISHYSVAKQSTA EEECCHHHHHCHHHH	15.35	22461510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NSG2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NSG2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NSG2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
S35F6_HUMAN	SLC35F6	physical	16169070
ZN768_HUMAN	ZNF768	physical	21900206
ECM1_HUMAN	ECM1	physical	28514442
ASAH1_HUMAN	ASAH1	physical	28514442
GRP78_HUMAN	HSPA5	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.