| UniProt ID | S35F6_HUMAN | |
|---|---|---|
| UniProt AC | Q8N357 | |
| Protein Name | Solute carrier family 35 member F6 | |
| Gene Name | SLC35F6 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 371 | |
| Subcellular Localization |
Mitochondrion. Lysosome membrane Multi-pass membrane protein. |
|
| Protein Description | Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter.. | |
| Protein Sequence | MAWTKYQLFLAGLMLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFSCLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGDLLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGTEGLFGFVILSLLLVPMYYIPAGSFSGNPRGTLEDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRTVVIWALSLALGWEAFHALQILGFLILLIGTALYNGLHRPLLGRLSRGRPLAEESEQERLLGGTRTPINDAS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MAWTKYQLFLA ----CCCHHHHHHHH | 29116813 | ||
| 6 | Phosphorylation | --MAWTKYQLFLAGL --CCCHHHHHHHHHH | 18083107 | ||
| 17 | Phosphorylation | LAGLMLVTGSINTLS HHHHHHHHCCHHHHC | 29116813 | ||
| 22 | Phosphorylation | LVTGSINTLSAKWAD HHHCCHHHHCHHHHH | 29116813 | ||
| 24 | Phosphorylation | TGSINTLSAKWADNF HCCHHHHCHHHHHHH | 29116813 | ||
| 70 | S-palmitoylation | AAFYLLRCRAAGQSD HHHHHHHHHHCCCCC | 29575903 | ||
| 110 | N-linked_Glycosylation | SLMYVALNMTSASSF HHHHHHHHCCCHHHH | UniProtKB CARBOHYD | ||
| 199 | Ubiquitination | IQMVLEEKFVYKHNV HHHHHHHHCHHHCCC | 23000965 | ||
| 203 | Ubiquitination | LEEKFVYKHNVHPLR HHHHCHHHCCCCCCH | 23000965 | ||
| 237 | Phosphorylation | MYYIPAGSFSGNPRG HHCCCCCCCCCCCCC | 29052541 | ||
| 239 | Phosphorylation | YIPAGSFSGNPRGTL CCCCCCCCCCCCCCH | 29052541 | ||
| 354 | Phosphorylation | GRPLAEESEQERLLG CCCCCCHHHHHHHHC | 29255136 | ||
| 363 | Phosphorylation | QERLLGGTRTPINDA HHHHHCCCCCCCCCC | 23401153 | ||
| 365 | Phosphorylation | RLLGGTRTPINDAS- HHHCCCCCCCCCCC- | 29255136 | ||
| 371 | Phosphorylation | RTPINDAS------- CCCCCCCC------- | 29255136 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of S35F6_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of S35F6_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of S35F6_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of S35F6_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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