NMI_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NMI_MOUSE
• UniProt AC: O35309
• Protein Name: N-myc-interactor
• Gene Name: Nmi
• Organism: Mus musculus (Mouse).
• Sequence Length: 314
• Subcellular Localization: Cytoplasm.
• Protein Description: May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription (By similarity). Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5 (By similarity)..
• Protein Sequence: MDADKDNIKQACDERSAEMDDMRGEQSMGLVHEIMSENKELDEEIKKLEAELQSDAREFQIKENVPEKKLKLTSVESPKDGCHFSNSSCSFQVSSQILYELQEGQALITFEKEEVAQNVISMGNHVVQMEGTPVKVSAHPVPLNTGVRFQVHVDISKMKINVTGIPDELSEEQTRDKLELSFCKSRNGGGEVESVDYDRKSRSAVITFVETGVVDKILKKKTYPLYMNQKCHSVAVSPCIERCLEKYQVFSAVSKKTVLLTGLEGIPVDEETGEDLLNIHFQRKNNGGGEVEVVKCSLDQSFAAYFKEEARETI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Ubiquitination	DADKDNIKQACDERS CCCHHHHHHHHHHHH	37.79	22790023
16	Phosphorylation	KQACDERSAEMDDMR HHHHHHHHHHHHHHH	26.91	-
77	Phosphorylation	LKLTSVESPKDGCHF EEECCCCCCCCCCCC	34.78	28285833
135	Ubiquitination	QMEGTPVKVSAHPVP EECCCEEEEEEEEEC	31.51	22790023
159	Ubiquitination	HVDISKMKINVTGIP EEEHHHCEEEEECCC	34.56	22790023
163	Phosphorylation	SKMKINVTGIPDELS HHCEEEEECCCCCCC	25.55	22871156
183	S-nitrosocysteine	DKLELSFCKSRNGGG HHEEEEEECCCCCCC	3.34	-
183	S-nitrosylation	DKLELSFCKSRNGGG HHEEEEEECCCCCCC	3.34	20925432
221	Ubiquitination	VDKILKKKTYPLYMN HHHHHHCCCCCCCCC	52.26	22790023
230	Ubiquitination	YPLYMNQKCHSVAVS CCCCCCCCHHEEEHH	28.98	22790023
237	Phosphorylation	KCHSVAVSPCIERCL CHHEEEHHHHHHHHH	12.34	23684622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NMI_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NMI_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NMI_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PKHO1_MOUSE	Plekho1	physical	17197158
IRF7_MOUSE	Irf7	physical	23956435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.