NCKP1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NCKP1_ARATH
• UniProt AC: Q5S2C4
• Protein Name: Protein NAP1
• Gene Name: NAP1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1425
• Protein Description: Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex..
• Protein Sequence: MANSRQYYPSQDESMSPTSVRSREWEGPSRWTEYLGPEMAASVSSTRSSKQIDGHVGGSTKALNIQWVVQMIEVADGLMAKMYRLNQILEYPDPVGHVFSEAFWKAGVFPNHPRICTLLSKKFPEHFSKLQLERIDKFSLDSLHDGAELHLQSLEPWIQLLLDLMAFREQALRLILDLSSTVITLLPHQNSLILHAFMDLFCAFVRVNLFAEKIPRKMLLQVYNLLHALSRNDRDCDFYHRLVQFIDSYDPPLKGLQEDLNFVSPRIGEVLEAVGPSIFLSADTRKLRNEGFLSPYHPRFPDILTNSAHPMRAQDLANVTSYREWVLLGYLVCPDELLRVTSIDIALVVLKENLVVTLFRDEVSLYQMVCEKEFGIGISFASADSINLTMQYILLHEDYQLYVLPRVLESKKMAKSGRTKQKEADLEYSVAKQVEKMISEVHEQALQLCDTIHRERRILLKQEIGRMVLFFTDQPSLLAPNIQMVFSALALAQSEVLWYFQHAGIASSRSKAARVIPVDIDPNDPTIGFLLDGMDRLCCLVRKYISAARGYALSYLSSSAGRIRYLMGTPGIVALDLDPTLKGLFQRIVQHLESIPKAQGENVSAITCDLSDFRKDWLSILMIVTSSRSSINIRHLEKATVSTGKEGLLSEGNAAYNWSRCVDELESQLSKHGSLKKLYFYHQHLTTVFRNTMFGPEGRPQHCCAWLSVASSFPECASLIIPEEVTKFGRDAVLYVESLIESIMGGLEGLINILDSEGGFGALESQLLPEQAAAYLNNASRISAPSVKSPRVVGGFTLPGHESYPENNKSIKMLEAAIQRLTNLCSILNDMEPICVINHVFVLREYMRECILGNFKRRFLTALQTDNDLQRPSVLESLIRRHMGIVHLAEQHVSMDLTQGIREILLTEAFSGPVSSLHTFEKPAEQQQTTGSAVEVVCNWYMDNIIKDVSGAGILFAPRHKYFKSTRPVGGYFAESVTDLKELQAFVRIFGGYGVDRLDRMMKVHTAALVNCIETSLRSNRELIEAAAASMHSGDRVERDASVRQIVDLDTVIGFCIEAGQALAFDDLLAEASGAVLEDNASLIHSMISGIVEHIPEEIPEKKEIRRIKGVANGVGVAGDHDSEWVRLILEEVGGANDNSWSLLPYFFASFMTSNAWNTTGFNIETGGFSNNIHCLARCISAVIAGSEYVRLQREYQQQHQSLSNGHHSSENLDSEFPPRVTAEASIKSSMLLFVKFAASIVLDSWSEANRSHLVAKLIFLDQLCEISPYLPRSSLESHVPYTILRSIYTQYYSNTPSTPLSTASPYHSPSVSLIHASPSMKNSTTPQRGSGSGSSSTAAPDSGYFKGSSSSLYGQEHYTESETGNSRNNENNNNNKQRGSSRRSGPLDYSSSHKGGSGSNSTGPSPLPRFAVSRSGPISYKQHN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	NSRQYYPSQDESMSP CCCCCCCCCCCCCCC	33.86	23776212
14	Phosphorylation	YYPSQDESMSPTSVR CCCCCCCCCCCCCCC	32.61	23776212
16	Phosphorylation	PSQDESMSPTSVRSR CCCCCCCCCCCCCCC	34.01	30291188
18	Phosphorylation	QDESMSPTSVRSREW CCCCCCCCCCCCCCC	32.33	23776212
19	Phosphorylation	DESMSPTSVRSREWE CCCCCCCCCCCCCCC	20.93	23776212
786	Phosphorylation	ASRISAPSVKSPRVV CCCCCCCCCCCCCEE	41.72	19880383
789	Phosphorylation	ISAPSVKSPRVVGGF CCCCCCCCCCEECCE	18.78	30291188
810	Phosphorylation	SYPENNKSIKMLEAA CCCCCCHHHHHHHHH	29.57	26091701
1089	Phosphorylation	SLIHSMISGIVEHIP HHHHHHHHHHHHHCC	17.52	28011693
1331	Phosphorylation	STTPQRGSGSGSSST CCCCCCCCCCCCCCC	31.79	25561503
1333	Phosphorylation	TPQRGSGSGSSSTAA CCCCCCCCCCCCCCC	36.88	25561503
1335	Phosphorylation	QRGSGSGSSSTAAPD CCCCCCCCCCCCCCC	23.86	25561503
1336	Phosphorylation	RGSGSGSSSTAAPDS CCCCCCCCCCCCCCC	34.92	25561503
1349	Phosphorylation	DSGYFKGSSSSLYGQ CCCCCCCCCCCCCCC	27.86	29654922
1350	Phosphorylation	SGYFKGSSSSLYGQE CCCCCCCCCCCCCCC	32.39	25561503
1359	Phosphorylation	SLYGQEHYTESETGN CCCCCCCCCCCCCCC	16.08	25561503
1360	Phosphorylation	LYGQEHYTESETGNS CCCCCCCCCCCCCCC	34.64	25561503
1362	Phosphorylation	GQEHYTESETGNSRN CCCCCCCCCCCCCCC	32.43	25561503
1364	Phosphorylation	EHYTESETGNSRNNE CCCCCCCCCCCCCCC	51.44	25561503
1367	Phosphorylation	TESETGNSRNNENNN CCCCCCCCCCCCCCC	37.42	25561503
1385	Phosphorylation	QRGSSRRSGPLDYSS CCCCCCCCCCCCCCC	43.59	23776212
1390	Phosphorylation	RRSGPLDYSSSHKGG CCCCCCCCCCCCCCC	20.38	23776212
1391	Phosphorylation	RSGPLDYSSSHKGGS CCCCCCCCCCCCCCC	25.65	23776212
1392	Phosphorylation	SGPLDYSSSHKGGSG CCCCCCCCCCCCCCC	30.17	23776212
1393	Phosphorylation	GPLDYSSSHKGGSGS CCCCCCCCCCCCCCC	24.23	23776212
1400	Phosphorylation	SHKGGSGSNSTGPSP CCCCCCCCCCCCCCC	29.33	25561503
1402	Phosphorylation	KGGSGSNSTGPSPLP CCCCCCCCCCCCCCC	36.12	25561503
1403	Phosphorylation	GGSGSNSTGPSPLPR CCCCCCCCCCCCCCC	58.31	25561503
1406	Phosphorylation	GSNSTGPSPLPRFAV CCCCCCCCCCCCCCC	40.17	25561503
1416	Phosphorylation	PRFAVSRSGPISYKQ CCCCCCCCCCCCCCC	41.22	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NCKP1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NCKP1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NCKP1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NCKP1_ARATH	GRL	physical	17267444
PIR_ARATH	PIR121	physical	17267444
P2C56_ARATH	ABI1	physical	17267444
P2C77_ARATH	ABI2	physical	17267444
RS61_ARATH	RPS6	physical	26241676
HDT2_ARATH	HD2B	physical	26241676

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.