NAP1A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NAP1A_ARATH
• UniProt AC: Q9SZI2
• Protein Name: Nucleosome assembly protein 1
• Gene Name: NAP1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 372
• Subcellular Localization: Nucleus. Cytoplasm. Predominantly located in cytoplasm. Shuttles between cytoplasm and nucleus depending on stage of the cell cycle. Farnelysation favors the location to the nucleus early in leaf development.
• Protein Description: May modulate chromatin structure by regulation of nucleosome assembly/disassembly (By similarity). Contributes to the regulation of cell proliferation and cell expansion. May function in nucleotide excision repair (NER). Involved in somatic homologous recombination..
• Protein Sequence: MSNDKDSFNVSDLTAALKDEDRAGLVNALKNKLQNLAGQRSDVLENLTPNVRKRVDALRDIQSQHDELEAKFREERAILEAKYQTLYQPLYVKRYEIVNGTTEVELAPEDDTKVDQGEEKTAEEKGVPSFWLTALKNNDVISEEVTERDEGALKYLKDIKWCKIEEPKGFKLEFFFDTNPYFKNTVLTKSYHMIDEDEPLLEKAMGTEIDWYPGKCLTQKILKKKPKKGSKNTKPITKLEDCESFFNFFSPPEVPDEDEDIDEERAEDLQNLMEQDYDIGSTIREKIIPRAVSWFTGEAMEAEDFEIDDDEEDDIDEDEDEEDEEDEEDDDDEDEEESKTKKKPSIGNKKGGRSQIVGEGKQDERPPECKQQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSNDKDSFN ------CCCCHHCCC		27531888
5	Acetylation	---MSNDKDSFNVSD ---CCCCHHCCCHHH		-
41	Phosphorylation	QNLAGQRSDVLENLT HHHHHCCHHHHHHCC		30291188
48	Phosphorylation	SDVLENLTPNVRKRV HHHHHHCCHHHHHHH		30291188
354	Phosphorylation	GNKKGGRSQIVGEGK CCCCCCCCCCCCCCC		25561503
369	Farnesylation	QDERPPECKQQ---- CCCCCCCHHCC----		17041028
369	Methylation	QDERPPECKQQ---- CCCCCCCHHCC----		17041028
369	Farnesylation	QDERPPECKQQ---- CCCCCCCHHCC----		17041028

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NAP1A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NAP1A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NAP1A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NAP1C_ARATH	NAP1;3	physical	21798944
NAP1A_ARATH	NAP1;1	physical	21798944
RS62_ARATH	EMB3010	physical	21798944
RL391_ARATH	AT4G31985	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.