dbPTM

RS62_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RS62_ARATH
UniProt AC	P51430
Protein Name	40S ribosomal protein S6-2
Gene Name	RPS6B
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	249
Subcellular Localization
Protein Description	May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA..
Protein Sequence	MKFNVANPTTGCQKKLEIDDDQKLRAFFDKRLSQEVSGDALGEEFKGYVFKIMGGCDKQGFPMKQGVLTPGRVRLLLHRGTPCFRGHGRRTGERRRKSVRGCIVSPDLSVLNLVIVKKGVSDLPGLTDTEKPRMRGPKRASKIRKLFNLGKEDDVRKYVNTYRRTFTNKKGKKVSKAPKIQRLVTPLTLQRKRARIADKKKRIAKANSDAADYQKLLASRLKEQRDRRSESLAKKRSRLSSAPAKPVAA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	KRLSQEVSGDALGEE HHHHCCCCCCCCCHH	30.15	23776212
69	Phosphorylation	PMKQGVLTPGRVRLL CCCCCCCCCCHHEEE	22.69	25561503
127	Phosphorylation	VSDLPGLTDTEKPRM CCCCCCCCCCCCCCC	46.95	30291188
185	Phosphorylation	PKIQRLVTPLTLQRK HHHHHHCCHHHHHHH	19.71	24894044
188	Phosphorylation	QRLVTPLTLQRKRAR HHHCCHHHHHHHHHH	23.27	24894044
208	Phosphorylation	KRIAKANSDAADYQK HHHHHHCCCHHHHHH	33.22	30407730
213	Phosphorylation	ANSDAADYQKLLASR HCCCHHHHHHHHHHH	11.65	25561503
229	Phosphorylation	KEQRDRRSESLAKKR HHHHHHHHHHHHHHH	32.22	23776212
231	Phosphorylation	QRDRRSESLAKKRSR HHHHHHHHHHHHHHH	34.57	23776212
237	Phosphorylation	ESLAKKRSRLSSAPA HHHHHHHHHHHCCCC	46.59	19880383
240	Phosphorylation	AKKRSRLSSAPAKPV HHHHHHHHCCCCCCC	24.28	19880383
241	Phosphorylation	KKRSRLSSAPAKPVA HHHHHHHCCCCCCCC	42.75	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RS62_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RS62_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RS62_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
NAP1C_ARATH	NAP1;3	physical	21798944

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RS62_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-237 AND SER-240, ANDMASS SPECTROMETRY.	19376835 [Abstract]