MTN2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MTN2_ARATH
• UniProt AC: Q7XA67
• Protein Name: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2
• Gene Name: MTN2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 254
• Protein Description: Enzyme of the methionine cycle that catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Contributes to the maintenance of AdoMet homeostasis and is required to sustain high rates of ethylene synthesis..
• Protein Sequence: MEGVMGQVEKRPISTIVFIVAMQKEAQPLINRLRLVEEVNTPFPKEVTWIMFKGMYKDLNINIVCPGKDSTLGVESVGTVPASLVTYASILAIQPDLIINAGTAGGFKAKGACISDVYVVSTVAFHDRRIPVPVLDIYGVGMRNTFPTPNLIKELNLKVGRLSTGDSMDMSPHDEESITANDATVKDMEGAAVAYVADIFKVPTILIKGVTDIVDGNRPTSEEFLENLAAVTAKLDESLTKVIDFISGKCLSDL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEGVMGQV -------CCCCCCCC	10.24	22223895

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MTN2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MTN2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MTN2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CNBL3_ARATH	CBL3	physical	26259190
MTN2_ARATH	MTN2	physical	26259190

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.