MTD1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MTD1_SCHPO
• UniProt AC: Q9P786
• Protein Name: Methylenetetrahydrofolate dehydrogenase [NAD(+)]
• Gene Name: mtd1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 320
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis..
• Protein Sequence: MSNTNKSEPNHSCKVVYASRVAETFVEQLKQHVNLFEFAPKLVGFLSNSDPAARMYADWTNKTCTEIGFQYELREVPKDDLEDAIVEANNDPSVNGIMIYFPVFNDGQDQYLQQVVSPDKDVEGLCHKYVMNMYHNIRHLDPEKTKKSILPCTPLAIVKILEYLGVYNKIINYGNRLYGKTITIVNRSEIVGRPLAALLANDGAKVYSVDIHNVQCFTRGAGIRSKKHDVADTNFKLEDVAPISDVIICGVPSANYKFPSNLVRDGAVCICFSSEKNFDAASLKEHAGIYVPSIGKVTIAMLLRNLIRLTSYQLNKPVDI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
148	Phosphorylation	DPEKTKKSILPCTPL CHHHCCCCCCCCCHH	30.80	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MTD1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MTD1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MTD1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MTD1_SCHPO	SPBC1711.04	physical	26771498
ASSY_SCHPO	arg12	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.