MSP1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MSP1_SCHPO
• UniProt AC: P87320
• Protein Name: Protein msp1, mitochondrial
• Gene Name: msp1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 903
• Subcellular Localization: Mitochondrion inner membrane ; Single-pass type II membrane protein ; Intermembrane side .
• Protein Description: Dynamin-related GTPase required for mitochondrial fusion. Coordinates interaction between the inner and outer mitochondrial membrane to promote the formation of the double membrane (By similarity)..
• Protein Sequence: MGISWFLSRFRIRTVAPSSFLKPRGLVYRPSQIRRRVSLLSLSGFHPYRAYSILGPKTPTAFNSANTVRFFSFSSISRLVFRSLRLPVAGFSLVAGGAAYIGAQVQRASDYTKDIFDKTFGILDSTWEKTRETVASVTNVQLPEISMPLWLEKILRLDEESAERRRVLQAERAKEHRSNSNDKQKSSDNDEDPNDTTVGIGAALAASILSVDSVDGEDTLTADEKRKLAQESKEDRMMLFTKKMIEIRNILQDIQDNNSAVTLPSIVVIGSQSSGKSSVLEAIVGHEFLPKGSNMVTRRPIELTLVHSADTAIPYGEFSGVQLGKITDFSKIQHILTDLNMAVPSSQGVDDNPIRLTIYASHIPNLSLIDLPGYIQIHSEDQPADLDMKISKLCEKYIREPNIILAVCAADVDLANSAALRASRRVDPLGLRTIGVVTKMDLVPPSKAISILHNNNYPLHYGYIGVISRIVPTGRFSAGQNLTDLVSTQENSYFSTHQQFADARIGNYLGIQSLRKCLINVLEYTMSKNLQHTADSIRTELEECNYQYKVQYNDRVLTADSYIAEGLDIFKAAFKEFTQKFGKSEVRDLLKSSLNEKVMDLLAERYWTDDDISNWSKHTNALDEHWKYKLDSCVSTLTRMGLGRVSTLLVTDSISKCIDEITKASPFADHPAAMQYIMNAAQDILRRRFHATSEQVENCVKPYKYDVEVNDDEWKSSRGQAEKLLQRELGLCQSALEKIKNAVGSRRMNQVLQYLEEQKTSSEPLPASYSTALLEQGRMLQYLKMREDILKLRISVLKSRACKHKEAKYTCPEIFLNAVSDKLVNTAVLFINIELLSEFYYQFPRELDQRLIHSLSSEQLNAFVNENPRLKSQLQLQHKRQCLELALQKINSLVILEQQADSD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
902	Phosphorylation	ILEQQADSD------ HHHHCCCCC------	48.51	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MSP1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MSP1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MSP1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDR1_SCHPO	cdr1	physical	9928955
DNM1_SCHPO	dnm1	genetic	27664110
FIS1_SCHPO	fis1	genetic	27664110
MDV1_SCHPO	caf4	genetic	27664110

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.