MOB3C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOB3C_HUMAN
• UniProt AC: Q70IA8
• Protein Name: MOB kinase activator 3C
• Gene Name: MOB3C
• Organism: Homo sapiens (Human).
• Sequence Length: 216
• Protein Description: May regulate the activity of kinases..
• Protein Sequence: MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Acetylation	CLKQVFAKDKTFRPR HHHHHHHCCCCCCCC	48.57	19657559
14	Phosphorylation	QVFAKDKTFRPRKRF HHHHCCCCCCCCCCC	34.70	-
25	Phosphorylation	RKRFEPGTQRFELYK CCCCCCCCHHHHHHH	27.56	28060719
37	Phosphorylation	LYKKAQASLKSGLDL HHHHHHHHHHCCCCH	25.01	28060719
75	Phosphorylation	FNRINLIYGTMAERC HHHHHHHHHHHHHHH	15.09	27642862
89	Phosphorylation	CSETSCPVMAGGPRY HCCCCCCCCCCCCCC	4.88	24719451
113	Phosphorylation	YRRPAKLSAPRYMAL HCCCCCCCHHHHHHH	35.20	24719451
165	Phosphorylation	LFRVFVHVYIHHFDS HHHHHHHHHHHHHHH	3.95	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOB3C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOB3C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOB3C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LATS1_HUMAN	LATS1	physical	19739119
LATS2_HUMAN	LATS2	physical	19739119
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.