| UniProt ID | MOB2_HUMAN | |
|---|---|---|
| UniProt AC | Q70IA6 | |
| Protein Name | MOB kinase activator 2 | |
| Gene Name | MOB2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 237 | |
| Subcellular Localization | Nucleus . Cytoplasm, perinuclear region . | |
| Protein Description | Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.. | |
| Protein Sequence | MDWLMGKSKAKPNGKKPAAEERKAYLEPEHTKARITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Acetylation | -MDWLMGKSKAKPNG -CCCCCCCCCCCCCC | 34.51 | 25953088 | |
| 11 | Ubiquitination | LMGKSKAKPNGKKPA CCCCCCCCCCCCCCC | 42.63 | 30230243 | |
| 23 | Ubiquitination | KPAAEERKAYLEPEH CCCHHHHHHHCCCHH | 44.67 | 24816145 | |
| 32 | Ubiquitination | YLEPEHTKARITDFQ HCCCHHCCCCCCCCC | 37.26 | 29967540 | |
| 42 | Ubiquitination | ITDFQFKELVVLPRE CCCCCHHEEEEEECE | 48.35 | 30230243 | |
| 54 | Ubiquitination | PREIDLNEWLASNTT ECEECHHHHHHHCCC | 51.68 | 24816145 | |
| 63 | Ubiquitination | LASNTTTFFHHINLQ HHHCCCCEEEECCCC | 5.29 | 29967540 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MOB2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MOB2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MOB2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| NRDC_HUMAN | NRD1 | physical | 16061636 | |
| STK38_HUMAN | STK38 | physical | 20624913 | |
| ST38L_HUMAN | STK38L | physical | 20624913 | |
| ST38L_HUMAN | STK38L | physical | 15067004 | |
| STK38_HUMAN | STK38 | physical | 15067004 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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