MIS18_SCHPO - dbPTM
MIS18_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MIS18_SCHPO
UniProt AC Q9P802
Protein Name Kinetochore protein mis18
Gene Name mis18
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 194
Subcellular Localization Cytoplasm . Nucleus . Chromosome, centromere . Chromosome, centromere, kinetochore .
Protein Description Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A. [PubMed: 15369671]
Protein Sequence MSQTETSHSGYIDFKKESQPSVFQCKKCFQIVGDSNAWVISHREYLSFTLSDAVENSVRVEDTFKRSDDGLCVYSELSCTRCNEVIGKVYNSTPIYLDDIRDMYTFSMDKLQAYQLGNKTVNPEGLTRYQVDLEMREDIIKLKSFCLSLYEKFELHDETLRSVKETISSLKKPKIEGKEGKKEKARTYSKRTRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSQTETSHS
------CCCCCCCCC
45.9024763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MIS18_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MIS18_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MIS18_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CENPA_SCHPOcnp1genetic
15369671
HAT2_SCHPOmis16physical
15369671
PHD1_SCHPOhos2genetic
17352737
YBC2_SCHPOmis19physical
24789708
YG7G_SCHPOmis20physical
24789708
HAT2_SCHPOmis16physical
24789708
HAT2_SCHPOmis16physical
24774534
YBC2_SCHPOmis19physical
24774534
YG7G_SCHPOmis20physical
24774534
MIS18_SCHPOmis18physical
24774534
RENT1_SCHPOupf1genetic
24774534
NMD2_SCHPOupf2genetic
24774534
UPF3_SCHPOupf3genetic
24774534
YB33_SCHPOebs1genetic
24774534
SNF22_SCHPOsnf22genetic
24774534
SNF5_SCHPOsnf5genetic
24774534
SOL1_SCHPOsol1genetic
24774534
MIS18_SCHPOmis18physical
26921242
MIS18_SCHPOmis18physical
26942680

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MIS18_SCHPO

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Related Literatures of Post-Translational Modification

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