| UniProt ID | MAGBI_HUMAN | |
|---|---|---|
| UniProt AC | Q96M61 | |
| Protein Name | Melanoma-associated antigen B18 | |
| Gene Name | MAGEB18 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 343 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.. | |
| Protein Sequence | MPRGQKSKLRAREKRHQARCENQDLGATQATVAEGESPSPAYLLFGDRPQNLPAAETPSIPEALQGAPSTTNAIAPVSCSSNEGASSQDEKSLGSSREAEGWKEDPLNKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKDKCHFNEILKRASEHMELALGVDLKEVDPIRHYYAFFSKLDLTYDETTSDEEKIPKTGLLMIALGVIFLNGNRAPEEAVWEIMNMMGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPNSDPPRYEFLWGPRAHAETSKMKVLEFVAKIHDTVPSAFPSCYEEALRDEEQRTQARAAARAHTAAMANARSRTTSSSFSHAK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 183 | Phosphorylation | FFSKLDLTYDETTSD HHHHCCCCCCCCCCC | 28.70 | 22817900 | |
| 187 | Phosphorylation | LDLTYDETTSDEEKI CCCCCCCCCCCHHHC | 28.80 | 22468782 | |
| 188 | Phosphorylation | DLTYDETTSDEEKIP CCCCCCCCCCHHHCC | 31.94 | 22468782 | |
| 189 | Phosphorylation | LTYDETTSDEEKIPK CCCCCCCCCHHHCCH | 50.90 | 22817900 | |
| 267 | Phosphorylation | PNSDPPRYEFLWGPR CCCCCCCCCCCCCCC | 19.46 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MAGBI_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MAGBI_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MAGBI_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| LNX1_HUMAN | LNX1 | physical | 20864041 | |
| GABP1_HUMAN | GABPB1 | physical | 19060904 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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