M3KCL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: M3KCL_HUMAN
• UniProt AC: P57077
• Protein Name: MAP3K7 C-terminal-like protein
• Gene Name: MAP3K7CL
• Organism: Homo sapiens (Human).
• Sequence Length: 242
• Protein Sequence: MVQLIAPLEVMWNEAADLKPLALSRRLECSGGIMAHYSPDLLGPEMESRYFAQVGLEHLASSSPPAFGFLKCLDYSISVLCSATSLAMLEDNPKVSKLATGDWMLTLKPKSITVPVEIPSSPLDDTPPEDSIPLVFPELDQQLQPLPPCHDSEESMEVFKQHCQIAEEYHEVKKEITLLEQRKKELIAKLDQAEKEKVDAAELVREFEALTEENRTLRLAQSQCVEQLEKLRIQYQKRQGSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
24	Phosphorylation	DLKPLALSRRLECSG CCHHHHHHCCEEECC		24719451
174	Acetylation	EEYHEVKKEITLLEQ HHHHHHHHHHHHHHH		25953088

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of M3KCL_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of M3KCL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of M3KCL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TAB3_HUMAN	TAB3	physical	16189514
CISH_HUMAN	CISH	physical	21988832
KAD8_HUMAN	AK8	physical	25416956
TAB3_HUMAN	TAB3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.