LSME2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LSME2_HUMAN
• UniProt AC: Q8N112
• Protein Name: Leucine-rich single-pass membrane protein 2
• Gene Name: LSMEM2
• Organism: Homo sapiens (Human).
• Sequence Length: 164
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MPSLAPDCPLLAMPEETQEDSVAPMMPSQRSRGPLAPNHVHEVCLHQVESISDLHSGAGTLRPYLTEEARPWDELLGVLPPSLCAQAGCSPVYRRGGFLLLLALLVLTCLVLALLAVYLSVLQSESLRILAHTLRTQEETLLKLRLASLSQLRRLNSSEAQAPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
136	Phosphorylation	ILAHTLRTQEETLLK HHHHHHCCCHHHHHH		26074081
140	Phosphorylation	TLRTQEETLLKLRLA HHCCCHHHHHHHHHH		26074081
148	Phosphorylation	LLKLRLASLSQLRRL HHHHHHHHHHHHHHH		26074081
150	Phosphorylation	KLRLASLSQLRRLNS HHHHHHHHHHHHHCC		26074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LSME2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LSME2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LSME2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
LSME1_HUMAN	LSMEM1	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.