LSME1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LSME1_HUMAN
• UniProt AC: Q8N8F7
• Protein Name: Leucine-rich single-pass membrane protein 1
• Gene Name: LSMEM1
• Organism: Homo sapiens (Human).
• Sequence Length: 131
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MTHSSQDTGSCGIQEDGKLYVVDSINDLNKLNLCPAGSQHLFPLEDKIPVLGTNSGNGSRSLFFVGLLIVLIVSLALVFFVIFLIVQTGNKMDDVSRRLTAEGKDIDDLKRINNMIVKRLNQLNQLDSEQN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	IQEDGKLYVVDSIND ECCCCEEEEEECCCC		22673903
24	Phosphorylation	GKLYVVDSINDLNKL CEEEEEECCCCCHHC		22673903
38	Phosphorylation	LNLCPAGSQHLFPLE CCCCCCCCCCEEECC		26437602
55 (in isoform 2)	Phosphorylation	-		23909892
74	Phosphorylation	LLIVLIVSLALVFFV HHHHHHHHHHHHHHH		22210691
96	Phosphorylation	GNKMDDVSRRLTAEG CCCHHHHHHHHHCCC		22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LSME1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LSME1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LSME1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.