dbPTM

LMLN_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LMLN_DROME
UniProt AC	Q9VH19
Protein Name	Leishmanolysin-like peptidase
Gene Name	Invadolysin
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	683
Subcellular Localization	Cytoplasm . Found in ring-like structures resembling invadopodia. In migrating cells it relocalizes from internal structures to the leading edge of cells.
Protein Description	Essential for the coordination of mitotic progression, and also plays a role in cell migration..
Protein Sequence	MAKTPPLRPHGNMAKFLAALGICSWLLVSATAHNCQHQHPKAHEVVHGVRIQLADSEDDSAGDPARHSVRRRSVAAEQPLRILLVYDESVYRLEEEKFNLINDTVLPEAVQFWEQALMVRETKGVIRLNRKCDSTQVYVKNGHTHCIDHCKATTMCGEVQVPDAHLDVCRVCNATGQNCRIDSNTQPGEGIENADFVFYVSARQTQRCFKGLTVAYAAHCQQEAALDRPIAGHANLCPESISTKPQELQTLISTVKHEILHALGFSVSLYAFFRDDDGKPRTPRKLDTGKPYLNEKLQIHQWSNETIRKVVRENWSVRGGHVNKVVDMMVTPRVIAEVRAHFNCNKLEGAELEDQGGEGTALTHWEKRILENEAMTGTHTQSPVFSRITLALMEDSGWYRANYSMATPLTWGKGLGCAFAMRSCKDWIQYNHARGRSIHPFCSKVKQDPLQTECTDDRNSVALCNLIRHEFELPKGYQNFDSLNHVKDGEEGFYGGSVSLADHCPYIQEFTWRSKNVIVRGSHCRFTENNPRPEKNFALESYGEGAKCFDHSESMWEERSCHQTREWQHWGSGCYKYDCFDGRLHILVGNYSYKCSFPGQKLSIRIAANGWLHKGAIMCPPCHELCGAQFAAQGKQCRPGEEPDPLNKYPRDNLACGAGSEKSRSVAIITAVLLLFGLRWGFS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of LMLN_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LMLN_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LMLN_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LMLN_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRP19_DROME	Srp19	physical	14605208
TNKS_DROME	Tnks	physical	14605208
NOSIP_DROME	CG6179	physical	14605208
PH4H_DROME	Hn	physical	14605208
KPBA_DROME	CG7766	physical	14605208
ATPA_DROME	blw	genetic	23943867
ATPA_DROME	blw	physical	23943867
ATP5H_DROME	ATPsyn-d	physical	23943867
ATPB_DROME	ATPsyn-beta	physical	23943867

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LMLN_DROME

Related Literatures of Post-Translational Modification