dbPTM

LAS1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LAS1_SCHPO
UniProt AC	O42936
Protein Name	Pre-rRNA-processing protein las1
Gene Name	las1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	470
Subcellular Localization	Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle pole.
Protein Description	Required for both pre-rRNA processing and heterochromatic gene silencing..
Protein Sequence	MDMKVVPWRLKEDFLYLMSCFYNEGQEGIPDLAALFRGVEIIQAWSTRGRIPHSVESTSQLVSSLISNDRSQKLALAVSISRFVSGLLDPIQQSQYAIPMAVLAKSIDLPTYFVELRHAITHEELPSLPVLRQAAQRALSWLYDHYWNPAATAESEDTYDYTETNELHKFEIKRKVKDLLKQWRSWRKVNVSANMFLPVEEHDYIQQFEALVQELVTTANLRLPYIPASFVDDEKDLDFAIETTNLDIVVSCFLEKRVLIPSRTMPISFFPKLKNVWLPLLQSIASKHSFFLPALFTTLWSEILEISQTVDSLVFLDLKEKEELTDKESAGCYLAKWYAYLMREAYTGQPWTSTLSVTQTDLASVLEICLQRSDPFTKIIIDELSILDKELENKFSPLFQYRSDMFDSRILDEQEFEDITLEQMKTELNKFSVRLNNIEAQADSSTMEFQGHVWYKPSVEPSPIGQIIES

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of LAS1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LAS1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LAS1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LAS1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RIX1_SCHPO	rix1	physical	21385875
IPI3_SCHPO	crb3	physical	21385875
GRC3_SCHPO	grc3	physical	21385875

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LAS1_SCHPO

Related Literatures of Post-Translational Modification