KIF3B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KIF3B_MOUSE
• UniProt AC: Q61771
• Protein Name: Kinesin-like protein KIF3B
• Gene Name: Kif3b
• Organism: Mus musculus (Mouse).
• Sequence Length: 747
• Subcellular Localization: Cytoplasm, cytoskeleton . Cell projection, cilium .
• Protein Description: Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity)..
• Protein Sequence: MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTSHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEDGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKNKIMNRSFFDDEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEPRYRAENIMLLELDMPSRTTRDYEGPAISPKVQAALDAALQDEDEIQVDASSFESTASRKPKARPKSGRKSGSSSSSSGNPASQFYPQSRGLVPK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MSKLKSSE -------CCCCCCCC	7.81	-
2	Acetylation	------MSKLKSSES ------CCCCCCCCC	46.85	-
181	Phosphorylation	VYVKDLSSFVTKSVK EEEECHHHHHHHHHH	30.91	21183079
333	Phosphorylation	ETLTTLRYANRAKNI HHHHHHHHHHHHHCC	16.02	29514104
546	Phosphorylation	KKLKKLFSKLQAVKA HHHHHHHHHHHHHHH	42.78	24719451
631	Phosphorylation	QMMKRPVSAVGYKRP HHHCCCCCCCCCCCC	21.66	29176673
671	Phosphorylation	ELDMPSRTTRDYEGP EECCCCCCCCCCCCC	30.44	29899451
672	Phosphorylation	LDMPSRTTRDYEGPA ECCCCCCCCCCCCCC	22.04	29899451
675	Phosphorylation	PSRTTRDYEGPAISP CCCCCCCCCCCCCCH	21.35	29899451
681	Phosphorylation	DYEGPAISPKVQAAL CCCCCCCCHHHHHHH	22.30	25521595
723	Phosphorylation	RPKSGRKSGSSSSSS CCCCCCCCCCCCCCC	42.41	25619855
725	Phosphorylation	KSGRKSGSSSSSSGN CCCCCCCCCCCCCCC	33.85	25619855
726	Phosphorylation	SGRKSGSSSSSSGNP CCCCCCCCCCCCCCC	37.45	25619855
727	Phosphorylation	GRKSGSSSSSSGNPA CCCCCCCCCCCCCCH	35.62	25619855
728	Phosphorylation	RKSGSSSSSSGNPAS CCCCCCCCCCCCCHH	30.39	25619855
729	Phosphorylation	KSGSSSSSSGNPASQ CCCCCCCCCCCCHHH	44.18	25619855
730	Phosphorylation	SGSSSSSSGNPASQF CCCCCCCCCCCHHHC	44.53	25619855
735	Phosphorylation	SSSGNPASQFYPQSR CCCCCCHHHCCCCCC	23.29	25619855

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KIF3B_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KIF3B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KIF3B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KIFA3_MOUSE	Kifap3	physical	15834408
CTNB1_MOUSE	Ctnnb1	physical	15834408
CADH2_MOUSE	Cdh2	physical	15834408
CTND1_MOUSE	Ctnnd1	physical	15834408

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.