KCD14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KCD14_HUMAN
• UniProt AC: Q9BQ13
• Protein Name: BTB/POZ domain-containing protein KCTD14
• Gene Name: KCTD14
• Organism: Homo sapiens (Human).
• Sequence Length: 255
• Protein Sequence: MWQGCAVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHFNIYSFTFTWW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	RPVGRMTSQTPLPQS CCCCCCCCCCCCCCC	23.78	28842319
18	Phosphorylation	VGRMTSQTPLPQSPR CCCCCCCCCCCCCCC	26.93	28857561
23	Phosphorylation	SQTPLPQSPRPRRPT CCCCCCCCCCCCCCC	22.42	28857561
30	Phosphorylation	SPRPRRPTMSTVVEL CCCCCCCCEEEEEEE	23.18	24043423
32	Phosphorylation	RPRRPTMSTVVELNV CCCCCCEEEEEEEEC	22.11	24043423
33	Phosphorylation	PRRPTMSTVVELNVG CCCCCEEEEEEEECC	20.11	24043423
38	Ubiquitination	MSTVVELNVGGEFHT EEEEEEEECCCEEEE	19.51	21963094
38	Ubiquitination	MSTVVELNVGGEFHT EEEEEEEECCCEEEE	19.51	-
45	Phosphorylation	NVGGEFHTTTLGTLR ECCCEEEECCHHHHC	27.14	24043423
46	Phosphorylation	VGGEFHTTTLGTLRK CCCEEEECCHHHHCC	16.08	24043423
47	Phosphorylation	GGEFHTTTLGTLRKF CCEEEECCHHHHCCC	25.09	24043423
50	Phosphorylation	FHTTTLGTLRKFPGS EEECCHHHHCCCCCH	26.88	24043423
68	Ubiquitination	EMFSSLAKASTDAEG HHHHHHHHCCCCCCC	48.43	21906983
86	Ubiquitination	IDRPSTYFRPILDYL CCCCCCCCHHHHHHH	8.30	-
86	Ubiquitination	IDRPSTYFRPILDYL CCCCCCCCHHHHHHH	8.30	27667366
90	Ubiquitination	STYFRPILDYLRTGQ CCCCHHHHHHHHCCC	3.82	23503661
106	Ubiquitination	PTQHIPEVYREAQFY CCCCCCHHHHHHCHH	4.59	-
106	Ubiquitination	PTQHIPEVYREAQFY CCCCCCHHHHHHCHH	4.59	23503661
116	Ubiquitination	EAQFYEIKPLVKLLE HHCHHCHHHHHHHHH	21.99	21906983
120	Ubiquitination	YEIKPLVKLLEDMPQ HCHHHHHHHHHHCHH	55.85	23503661
136	Ubiquitination	FGEQVSRKQFLLQVP HHHHCCCHHHEEECC	37.58	23503661
162	Phosphorylation	LARAEAITARKSSVL HHHHHHHHHCCCCEE	27.70	-
166	Ubiquitination	EAITARKSSVLVCLV HHHHHCCCCEEEEEE	21.81	29967540
170	Ubiquitination	ARKSSVLVCLVETEE HCCCCEEEEEEECCC	1.91	29967540
192	Ubiquitination	VLCFLQDKKMFKSVV HHHHHCCHHHHHHHH	32.93	29967540
196	Ubiquitination	LQDKKMFKSVVKFGP HCCHHHHHHHHHHCC	38.55	29967540
197	Ubiquitination	QDKKMFKSVVKFGPW CCHHHHHHHHHHCCC	22.37	29967540
200	Ubiquitination	KMFKSVVKFGPWKAV HHHHHHHHHCCCEEE	42.31	29967540
209	Acetylation	GPWKAVLDNSDLMHC CCCEEEECCCCHHHH	46.09	-
211	Phosphorylation	WKAVLDNSDLMHCLE CEEEECCCCHHHHHH	31.61	24719451
222	Ubiquitination	HCLEMDIKAQGYKVF HHHHHHHHHCCCEEE	30.32	29967540
226	Phosphorylation	MDIKAQGYKVFSKFY HHHHHCCCEEEEEEE	7.59	24719451
227	Ubiquitination	DIKAQGYKVFSKFYL HHHHCCCEEEEEEEE	43.56	29967540
239	Acetylation	FYLTYPTKRNEFHFN EEEECCCCCCEEEEE	49.04	22424773

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KCD14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KCD14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KCD14_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KCD14_HUMAN	KCTD14	physical	25416956
ACSF3_HUMAN	ACSF3	physical	26186194
GCP6_HUMAN	TUBGCP6	physical	26186194
ACSF3_HUMAN	ACSF3	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.