JUND_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: JUND_MOUSE
• UniProt AC: P15066
• Protein Name: Transcription factor jun-D
• Gene Name: Jund
• Organism: Mus musculus (Mouse).
• Sequence Length: 341
• Subcellular Localization: Nucleus.
• Protein Description: Transcription factor binding AP-1 sites..
• Protein Sequence: METPFYGEEALSGLAAGASSVAGATGAPGGGGFAPPGRAFPGAPPTSSMLKKDALTLSLAEQGAAGLKPGSATAPSALRPDGAPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSTQFLYPKVAASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAPPAPADLAATPGATETPVYANLSSFAGGAGPPGGAATVAFAAEPVPFPPPPGALGPPPPPHPPRLAALKDEPQTVPDVPSFGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
56	Phosphorylation	MLKKDALTLSLAEQG HHHHHHHHHHHHHHH	18.93	25777480
58	Phosphorylation	KKDALTLSLAEQGAA HHHHHHHHHHHHHCC	21.94	25777480
71	Phosphorylation	AAGLKPGSATAPSAL CCCCCCCCCCCCHHC	30.85	25777480
73	Phosphorylation	GLKPGSATAPSALRP CCCCCCCCCCHHCCC	40.58	25777480
76	Phosphorylation	PGSATAPSALRPDGA CCCCCCCHHCCCCCC	37.15	25777480
90	Phosphorylation	APDGLLASPDLGLLK CCCCCCCCCCCCHHH	20.93	26239621
100	Phosphorylation	LGLLKLASPELERLI CCHHHHCCHHHHHHH	29.37	27087446
110	Phosphorylation	LERLIIQSNGLVTTT HHHHHECCCCCEECC	23.58	23984901
115	Phosphorylation	IQSNGLVTTTPTSTQ ECCCCCEECCCCCCH	29.96	23984901
116	Phosphorylation	QSNGLVTTTPTSTQF CCCCCEECCCCCCHH	24.25	26745281
117	Phosphorylation	SNGLVTTTPTSTQFL CCCCEECCCCCCHHC	18.40	26745281
119	Phosphorylation	GLVTTTPTSTQFLYP CCEECCCCCCHHCCC	42.17	26745281
120	Phosphorylation	LVTTTPTSTQFLYPK CEECCCCCCHHCCCC	22.78	26745281
121	Phosphorylation	VTTTPTSTQFLYPKV EECCCCCCHHCCCCC	26.31	24453211
131	Phosphorylation	LYPKVAASEEQEFAE CCCCCCCCHHHHHHH	31.74	25338131
239	Phosphorylation	ALKDEPQTVPDVPSF HCCCCCCCCCCCCCC	44.73	24925903
245	Phosphorylation	QTVPDVPSFGDSPPL CCCCCCCCCCCCCCC	41.53	24925903
249	Phosphorylation	DVPSFGDSPPLSPID CCCCCCCCCCCCCCC	28.88	24925903
253	Phosphorylation	FGDSPPLSPIDMDTQ CCCCCCCCCCCCCHH	26.11	27087446
259	Phosphorylation	LSPIDMDTQERIKAE CCCCCCCHHHHHHHH	26.20	24925903

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
90	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
100	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
100	S	Phosphorylation	Kinase	MAPK8	Q91Y86	Uniprot
117	T	Phosphorylation	Kinase	MAPK1	P28482	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of JUND_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of JUND_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BATF3_MOUSE	Batf3	physical	20211142
MEN1_MOUSE	Men1	physical	15563473
SIR1_MOUSE	Sirt1	physical	18676681

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.