IFT1B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IFT1B_HUMAN
• UniProt AC: Q5T764
• Protein Name: Interferon-induced protein with tetratricopeptide repeats 1B
• Gene Name: IFIT1B
• Organism: Homo sapiens (Human).
• Sequence Length: 474
• Protein Sequence: MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAADLNPIF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	IQFLDTKYNVGIHNL HHHHCCCCCCCHHHH	19.71	-
60	Phosphorylation	GIHNLLAYVKHLKGQ CHHHHHHHHHHHCCC	15.25	-
226	Ubiquitination	IRVLLALKLQDEGQE HHHHHHHHCCCCCCH	38.20	-
269	Ubiquitination	RRKGSVDKALELLKM HHCCCHHHHHHHHHH	53.36	-
404	Acetylation	KAITHYLKGLKIEKM HHHHHHHHCCCHHHC	55.84	30589437
407	Acetylation	THYLKGLKIEKMSHS HHHHHCCCHHHCCCC	58.44	30589443
439	Phosphorylation	QNVRVVESVSLLGLI CCCCHHHHHHHHHHH	12.85	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IFT1B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IFT1B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IFT1B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HERC1_HUMAN	HERC1	physical	28514442
MOCOS_HUMAN	MOCOS	physical	28514442
PRP16_HUMAN	DHX38	physical	28514442
MAP1A_HUMAN	MAP1A	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.