HUTI_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HUTI_HUMAN
• UniProt AC: Q96NU7
• Protein Name: Probable imidazolonepropionase
• Gene Name: AMDHD1
• Organism: Homo sapiens (Human).
• Sequence Length: 426
• Protein Sequence: MASGHSLLLENAQQVVLVCARGERFLARDALRSLAVLEGASLVVGKDGFIKAIGPADVIQRQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIHFTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARRELDIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDLDSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARCSAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMPEALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKGKLIYKT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Ubiquitination	VGKDGFIKAIGPADV ECCCCHHHCCCHHHH	31.52	21906983
159	Phosphorylation	LVECKSGYGLDLETE EEECCCCCCCCHHHH	22.93	22468782
165	Phosphorylation	GYGLDLETELKMLRV CCCCCHHHHHHHHHH	54.65	50564927
301	Phosphorylation	AMATARCSAILLPTT HHHHHHCCEEECCCH	16.88	29083192
307	Phosphorylation	CSAILLPTTAYMLRL CCEEECCCHHHHHHC	24.83	22210691
308	Phosphorylation	SAILLPTTAYMLRLK CEEECCCHHHHHHCC	17.53	22210691
310	Phosphorylation	ILLPTTAYMLRLKQP EECCCHHHHHHCCCH	8.45	22210691
367	Phosphorylation	PEALAAATINAAYAL HHHHHHHHHHHHHHH	15.27	26503514
404	Phosphorylation	SRWEHLIYQFGGHHE CCCCEEEHHCCCCHH	12.26	7331783
415	Phosphorylation	GHHELIEYVIAKGKL CCHHHHHHHHHCCCE	7.08	7331793

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HUTI_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HUTI_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HUTI_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KLH23_HUMAN	KLHL23	physical	26186194
IF1AX_HUMAN	EIF1AX	physical	26186194
KLH23_HUMAN	KLHL23	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.