HSFX1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HSFX1_HUMAN
• UniProt AC: Q9UBD0
• Protein Name: Heat shock transcription factor, X-linked
• Gene Name: HSFX1
• Organism: Homo sapiens (Human).
• Sequence Length: 423
• Subcellular Localization: Nucleus . Cytoplasm .
• Protein Sequence: MEDKRSLSMARCEERNSRGQDHGLERVPFPPQLQSETYLHPADPSPAWDDPGSTGSPNLRLLTEEIAFQPLAEEASFRRPHPDGDVPPQGEDNLLSLPFPQKLWRLVSSNQFSSIWWDDSGACRVINQKLFEKEILKRDVAHKVFATTSIKSFFRQLNLYGFRKRRQCTFRTFTRIFSAKRLVSILNKLEFYCHPYFQRDSPHLLVRMKRRVGVKSAPRHQEEDKPEAAGSCLAPADTEQQDHTSPNENDQVTPQHREPAGPNTQIRSGSAPPATPVMVPDSAVASDNSPVTQPAGEWSEGSQAHVTPVAAVPGPAALPFLYVPGSPTQMNSYGPVVALPTASRSTLAMDTTGLPAPGMLPFCHLWVPVTLVAAGAAQPAASMVMFPHLPALHHHCPHSHRTSQYMPASDGPQAYPDYADQST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	O-linked_Glycosylation	MEDKRSLSMARCEER CCCHHHHHHHHHHHH	16.19	30379171
96	Phosphorylation	QGEDNLLSLPFPQKL CCCCCCCCCCCCHHH	36.84	-
137	Ubiquitination	LFEKEILKRDVAHKV HHHHHHHHHHHHHHH	52.81	-
152	Phosphorylation	FATTSIKSFFRQLNL HCHHHHHHHHHHHCH	28.13	24719451
184	Phosphorylation	FSAKRLVSILNKLEF HCHHHHHHHHHHHHH	26.42	24719451
201	Phosphorylation	HPYFQRDSPHLLVRM CHHHCCCCCCHHHHH	19.19	-
215	Sumoylation	MKRRVGVKSAPRHQE HHHHHCCCCCCCCCC	34.66	-
215	Sumoylation	MKRRVGVKSAPRHQE HHHHHCCCCCCCCCC	34.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HSFX1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HSFX1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HSFX1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCD57_HUMAN	CCDC57	physical	25036637
SYIM_HUMAN	IARS2	physical	25036637
F192A_HUMAN	FAM192A	physical	25036637
CSPG2_HUMAN	VCAN	physical	25036637

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.