dbPTM

HMSH_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HMSH_DROME
UniProt AC	Q03372
Protein Name	Muscle segmentation homeobox
Gene Name	Dr
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	515
Subcellular Localization	Nucleus.
Protein Description	Plays a key role in the specification of proneural and promuscular cluster formation. Required for the specification of dorsal and lateral muscle progenitor cells..
Protein Sequence	MLKLSPASMTVTGLRQTMTSPTVPPSSNTPAGNLIITSSSSNSGSNSGSNMSSGNMTSSNLTNLSPSHPAGLNALASPTSPSALLLAHQQHLLQQHQQHQQQQQQQQQAAALQLAAVHPPAHHLHKTTSRLSNFSVASLLADTRPRTPPNQAADGPQNLTSSAATSPISQASSTPPPPPASAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQQQADARANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQEAEIEKIKMAALGRGAPGAQWAMAGYFHPSLMHLG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of HMSH_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HMSH_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HMSH_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HMSH_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
AMOS_DROME	amos	genetic	8252627
ETIF1_DROME	CG17737	physical	25242320

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HMSH_DROME

Related Literatures of Post-Translational Modification