GWD1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GWD1_ARATH
• UniProt AC: Q9SAC6
• Protein Name: Alpha-glucan water dikinase 1, chloroplastic
• Gene Name: GWD1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1399
• Subcellular Localization: Plastid, chloroplast . Starch granules.
• Protein Description: Mediates the incorporation of phosphate into starch-like alpha-glucan, mostly at the C-6 position of glucose units. Acts as an overall regulator of starch mobilization. Required for starch degradation, suggesting that the phosphate content of starch regulates its degradability..
• Protein Sequence: MSNSVVHNLLNRGLIRPLNFEHQNKLNSSVYQTSTANPALGKIGRSKLYGKGLKQAGRSLVTETGGRPLSFVPRAVLAMDPQAAEKFSLDGNIDLLVEVTSTTVREVNIQIAYTSDTLFLHWGAILDNKENWVLPSRSPDRTQNFKNSALRTPFVKSGGNSHLKLEIDDPAIHAIEFLIFDESRNKWYKNNGQNFHINLPTERNVKQNVSVPEDLVQIQAYLRWERKGKQMYNPEKEKEEYEAARTELREEMMRGASVEDLRAKLLKKDNSNESPKSNGTSSSGREEKKKVSKQPERKKNYNTDKIQRKGRDLTKLIYKHVADFVEPESKSSSEPRSLTTLEIYAKAKEEQETTPVFSKKTFKLEGSAILVFVTKLSGKTKIHVATDFKEPVTLHWALSQKGGEWLDPPSDILPPNSLPVRGAVDTKLTITSTDLPSPVQTFELEIEGDSYKGMPFVLNAGERWIKNNDSDFYVDFAKEEKHVQKDYGDGKGTAKHLLDKIADLESEAQKSFMHRFNIAADLVDEAKSAGQLGFAGILVWMRFMATRQLVWNKNYNVKPREISKAQDRLTDLLQDVYASYPEYRELLRMIMSTVGRGGEGDVGQRIRDEILVIQRKNDCKGGIMEEWHQKLHNNTSPDDVVICQALMDYIKSDFDLSVYWKTLNDNGITKERLLSYDRAIHSEPNFRGEQKDGLLRDLGHYMRTLKAVHSGADLESAIQNCMGYQDDGEGFMVGVQINPVSGLPSGYPDLLRFVLEHVEEKNVEPLLEGLLEARQELRPLLLKSHDRLKDLLFLDLALDSTVRTAIERGYEQLNDAGPEKIMYFISLVLENLALSSDDNEDLIYCLKGWQFALDMCKSKKDHWALYAKSVLDRSRLALASKAERYLEILQPSAEYLGSCLGVDQSAVSIFTEEIIRAGSAAALSSLVNRLDPVLRKTANLGSWQVISPVEVVGYVIVVDELLTVQNKTYDRPTIIVANRVRGEEEIPDGAVAVLTPDMPDVLSHVSVRARNGKICFATCFDSGILSDLQGKDGKLLSLQPTSADVVYKEVNDSELSSPSSDNLEDAPPSISLVKKQFAGRYAISSEEFTSDLVGAKSRNIGYLKGKVPSWVGIPTSVALPFGVFEKVISEKANQAVNDKLLVLKKTLDEGDQGALKEIRQTLLGLVAPPELVEELKSTMKSSDMPWPGDEGEQRWEQAWAAIKKVWASKWNERAYFSTRKVKLDHDYLCMAVLVQEVINADYAFVIHTTNPSSGDSSEIYAEVVKGLGETLVGAYPGRSLSFICKKNNLDSPLVLGYPSKPIGLFIRRSIIFRSDSNGEDLEGYAGAGLYDSVPMDEEDQVVLDYTTDPLITDLSFQKKVLSDIARAGDAIEKLYGTAQDIEGVIRDGKLYVVQTRPQV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
76	Acetylation	LSFVPRAVLAMDPQA CCCCCHHHEECCHHH	3.55	22223895
157	Phosphorylation	LRTPFVKSGGNSHLK CCCCCEECCCCCCEE	46.78	25561503
161	Phosphorylation	FVKSGGNSHLKLEID CEECCCCCCEEEEEC	33.21	19880383
201	Phosphorylation	NFHINLPTERNVKQN CCEEECCCCCCCCCC	51.23	25561503
271	Phosphorylation	KLLKKDNSNESPKSN HHHHCCCCCCCCCCC	52.70	25561503
274	Phosphorylation	KKDNSNESPKSNGTS HCCCCCCCCCCCCCC	41.71	25561503
280	Phosphorylation	ESPKSNGTSSSGREE CCCCCCCCCCCCHHH	29.68	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GWD1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GWD1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GWD1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUMO3_ARATH	SUMO3	physical	20855607
SUMO1_ARATH	SUMO1	physical	20855607

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.