GTR14_HUMAN - dbPTM
GTR14_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GTR14_HUMAN
UniProt AC Q8TDB8
Protein Name Solute carrier family 2, facilitated glucose transporter member 14
Gene Name SLC2A14
Organism Homo sapiens (Human).
Sequence Length 520
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description Facilitative glucose transporter (By similarity). May have a specific function related to spermatogenesis..
Protein Sequence MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMGMNSIEPAKETTTNV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8 (in isoform 2)Phosphorylation-16.3925278378
16 (in isoform 2)Phosphorylation-2.6425278378
19 (in isoform 2)Phosphorylation-3.8225278378
22 (in isoform 2)Phosphorylation-31.7325278378
67N-linked_GlycosylationTIIKEFINKTLTDKA
HHHHHHHHHHHHHCC		36.26UniProtKB CARBOHYD
140PhosphorylationGLCKIAESVEMLILG
HHHHHHHHHHHHHHH		17.8520068231
158UbiquitinationIGLFCGLCTGFVPMY
HHHHHHHHCCCCCCC		1.81-
158UbiquitinationIGLFCGLCTGFVPMY
HHHHHHHHCCCCCCC		1.8121963094
168UbiquitinationFVPMYIGEISPTALR
CCCCCCCCCCHHHHH		30.64-
168UbiquitinationFVPMYIGEISPTALR
CCCCCCCCCCHHHHH		30.6421963094
244UbiquitinationLINRKKEENATRILQ
EEECCHHHHHHHHHH		62.1321963094
254UbiquitinationTRILQRLWGTQDVSQ
HHHHHHHHCCCCHHH		15.2421963094
256PhosphorylationILQRLWGTQDVSQDI
HHHHHHCCCCHHHHH		15.2619664994
260PhosphorylationLWGTQDVSQDIQEMK
HHCCCCHHHHHHHHH		30.3520068231
267UbiquitinationSQDIQEMKDESARMS
HHHHHHHHHHHHHHC		58.5521963094
268UbiquitinationQDIQEMKDESARMSQ
HHHHHHHHHHHHHCH		54.4921963094
270PhosphorylationIQEMKDESARMSQEK
HHHHHHHHHHHCHHH		31.1721406692
274PhosphorylationKDESARMSQEKQVTV
HHHHHHHCHHHCCHH		29.6321406692
277UbiquitinationSARMSQEKQVTVLEL
HHHHCHHHCCHHHHH		42.2921963094
278UbiquitinationARMSQEKQVTVLELF
HHHCHHHCCHHHHHH		35.0521963094
282UbiquitinationQEKQVTVLELFRVSS
HHHCCHHHHHHHHCC		3.2821963094
292UbiquitinationFRVSSYRQPIIISIV
HHHCCCCCCHHHHHH		25.8821963094
357PhosphorylationVERAGRRTLHMIGLG
HHHHCCCCEEEECCC		21.47-
376PhosphorylationCSTLMTVSLLLKNHY
HHHHHHHHHHHHHCC		12.25-
405UbiquitinationVACFEIGPGPIPWFI
HHHHHHCCCCCCCHH		51.5632142685
491UbiquitinationDITRAFEGQAHGADR
HHHHHHCCCCCCCCC		24.4232142685
499PhosphorylationQAHGADRSGKDGVMG
CCCCCCCCCCCCCCC		51.2224173317
509PhosphorylationDGVMGMNSIEPAKET
CCCCCCCCCCCCCCC		21.3130622161
514UbiquitinationMNSIEPAKETTTNV-
CCCCCCCCCCCCCC-		67.3332142685
516PhosphorylationSIEPAKETTTNV---
CCCCCCCCCCCC---		37.9130622161
517PhosphorylationIEPAKETTTNV----
CCCCCCCCCCC----		19.9130622161
518PhosphorylationEPAKETTTNV-----
CCCCCCCCCC-----		41.2130622161
529Ubiquitination----------------
----------------		32142685
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GTR14_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GTR14_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GTR14_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GTR3_HUMANSLC2A3physical
28514442
EPN1_HUMANEPN1physical
28514442
HBB_HUMANHBBphysical
28514442
SMAP2_HUMANSMAP2physical
28514442
WDR73_HUMANWDR73physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GTR14_HUMAN

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Related Literatures of Post-Translational Modification

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