GRIP_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GRIP_ARATH
• UniProt AC: Q8S2T0
• Protein Name: Protein GRIP
• Gene Name: GRIP
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 788
• Subcellular Localization: Golgi apparatus . Locates to the trans-Golgi or to the trans-Golgi network (TGN).
• Protein Description: Golgi matrix protein playing a role in tethering of vesicles to Golgi membranes and in maintaining the overall structure of the Golgi apparatus..
• Protein Sequence: MSEDKESDVVGEEEESHVIKEDKELNDASNETLTENGDQLLQMIAELRLENDFLRSQFEGLKDEVAQGRSLQKAEQVEADSAQLKQLQEQVASLSREIDVEKQTRVAAEQALEHLREAYSEADAKSQEYSSKFSQVEQKLDQEIKERDEKYADLDAKFTRLHKRAKQRIQEIQKEKDDLDARFREVNETAERASSQHSSMQQELERTRQQANEALKAMDAERQQLRSANNKLRDTIEELRGSLQPKENKIETLQQSLLDKDQILEDLKKQLQAVEERKQIAVTELSAKHQKNLEGLEAQVVDALSERDKAAETISSLQVLLAEKESKIAEMEAAATGEAARLRAAAETLKGELAHLKSENEKEKETWEASCDALKSKLEIAESNYLQAEIEVAKMRSQLGSEMSMQTQILSTKDAELKGAREEINRLQSEFSSYKIRAHALLQKKDMELAAAKDSEQIKSLEEALKEAEKEVYLVSAERDRAQQDLQSALASLEKELEERAGALKDASEQIKSLEVKLDSTVARNQAEKQAWEEDLRVLEETWRRRCEALTAQNEASPAEGIEKELENAKLRNKRMKEEHESVRELADRLIEEKDREISRLVDEMTNLRKSMESKPVWNKSPSQVHHYGNNNTESQQQDVSNLSTSAAEHQILILARQQAQREEELAQTQRHILALQEEIEELERENRLHSQQEAVLKTELREMERKQKREGVDMTYLKNVILKLLETGEVEALLPVVGMLLQFSPEEIQKCQQAYHSSTTAATTTEATPSPASEGSGLSVFSRFSFS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSEDKESDV ------CCCCCCCCC	55.28	30407730
7	Phosphorylation	-MSEDKESDVVGEEE -CCCCCCCCCCCCHH	41.25	30407730
316	Phosphorylation	KAAETISSLQVLLAE HHHHHHHHHHHHHHH	20.97	28011693
331	Sulfoxidation	KESKIAEMEAAATGE HHHHHHHHHHHHHHH	2.91	23289948
401	Phosphorylation	KMRSQLGSEMSMQTQ HHHHHHCCHHHHHHH	38.42	19880383
404	Phosphorylation	SQLGSEMSMQTQILS HHHCCHHHHHHHHHH	12.04	19880383
407	Phosphorylation	GSEMSMQTQILSTKD CCHHHHHHHHHHHHH	14.67	19880383
542	Phosphorylation	DLRVLEETWRRRCEA HHHHHHHHHHHHHHH	18.20	25368622
621	Phosphorylation	SKPVWNKSPSQVHHY CCCCCCCCHHHCCCC	26.94	26811356
623	Phosphorylation	PVWNKSPSQVHHYGN CCCCCCHHHCCCCCC	52.50	27545962
628	Phosphorylation	SPSQVHHYGNNNTES CHHHCCCCCCCCCHH	13.48	27545962
633	Phosphorylation	HHYGNNNTESQQQDV CCCCCCCCHHHHHHH	38.85	27545962
635	Phosphorylation	YGNNNTESQQQDVSN CCCCCCHHHHHHHHH	31.11	27545962
641	Phosphorylation	ESQQQDVSNLSTSAA HHHHHHHHHCCHHHH	40.10	27545962
644	Phosphorylation	QQDVSNLSTSAAEHQ HHHHHHCCHHHHHHH	25.27	27545962
645	Phosphorylation	QDVSNLSTSAAEHQI HHHHHCCHHHHHHHH	26.08	27545962
646	Phosphorylation	DVSNLSTSAAEHQIL HHHHCCHHHHHHHHH	23.31	27545962

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GRIP_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GRIP_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GRIP_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ARF3_ARATH	ARF3	physical	16830178
ARF3_ARATH	ARF3	physical	16236155
RAH1B_ARATH	RAB6A	physical	19490533
GOGC5_ARATH	GC5	physical	19490533
DNJ16_ARATH	ARL1	physical	19490533
CASP_ARATH	CASP	physical	19490533
GRIP_ARATH	ATGRIP	physical	24901770

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.