GRF3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GRF3_ARATH
• UniProt AC: Q9SJR5
• Protein Name: Growth-regulating factor 3
• Gene Name: GRF3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 398
• Subcellular Localization: Nucleus .
• Protein Description: Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium..
• Protein Sequence: MDLQLKQWRSQQQQQHQTESEEQPSAAKIPKHVFDQIHSHTATSTALPLFTPEPTSSKLSSLSPDSSSRFPKMGSFFSWAQWQELELQALIYRYMLAGAAVPQELLLPIKKSLLHLSPSYFLHHPLQHLPHYQPAWYLGRAAMDPEPGRCRRTDGKKWRCSRDVFAGHKYCERHMHRGRNRSRKPVETPTTVNATATSMASSVAAAATTTTATTTSTFAFGGGGGSEEVVGQGGSFFFSGSSNSSSELLHLSQSCSEMKQESNNMNNKRPYESHIGFSNNRSDGGHILRPFFDDWPRSSLQEADNSSSPMSSATCLSISMPGNSSSDVSLKLSTGNEEGARSNNNGRDQQNMSWWSGGGSNHHHHNMGGPLAEALRSSSSSSPTSVLHQLGVSTQAFH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
60	Phosphorylation	EPTSSKLSSLSPDSS CCCCHHHHHCCCCCC		25561503
61	Phosphorylation	PTSSKLSSLSPDSSS CCCHHHHHCCCCCCC		29654922
63	Phosphorylation	SSKLSSLSPDSSSRF CHHHHHCCCCCCCCC		29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GRF3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GRF3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GRF3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GIF1_ARATH	AN3	physical	24285851
GIF2_ARATH	GIF2	physical	24285851
GIF3_ARATH	GIF3	physical	24285851

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.