| UniProt ID | GO45_MOUSE | |
|---|---|---|
| UniProt AC | Q8R2X8 | |
| Protein Name | Golgin-45 | |
| Gene Name | Blzf1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 403 | |
| Subcellular Localization | Golgi apparatus lumen. Nucleus. Cytoplasm. Also found in the nucleus and in the cytoplasm.. | |
| Protein Description | Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.. | |
| Protein Sequence | MEKMTTLKSSENKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKKVSSDSPGVLQLGKILNERTVEVEAVRIFVPKAAITHDIPTKNTKVKSLGHHREELHNQAEVVTDPRKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEINRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQRQNRDAQSAIQDLLSEREQFRQEMTSTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHGLAQAIHAHLLGNVGISHQKKIPTTVEFCSTPAEKMAEKVLRILDPVACTESSPDNQFAESSPTTLLTTKKNIGRFHPYTRYENITFNCCNHCQGELIAL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MEKMTTLKSSEN ---CCCCCCCCCCCC | 39.79 | 28576409 | |
| 17 | Phosphorylation | SENKGILTSTPIRGA CCCCCCEECCCCCCC | 28.74 | 28066266 | |
| 18 | Phosphorylation | ENKGILTSTPIRGAG CCCCCEECCCCCCCC | 28.83 | 28066266 | |
| 19 | Phosphorylation | NKGILTSTPIRGAGD CCCCEECCCCCCCCC | 19.94 | 28066266 | |
| 53 | Phosphorylation | INQHVLPSPRKKVSS CCCCCCCCCCCCCCC | 32.93 | 30352176 | |
| 59 | Phosphorylation | PSPRKKVSSDSPGVL CCCCCCCCCCCCCHH | 36.99 | 27600695 | |
| 60 | Phosphorylation | SPRKKVSSDSPGVLQ CCCCCCCCCCCCHHH | 45.13 | 28066266 | |
| 62 | Phosphorylation | RKKVSSDSPGVLQLG CCCCCCCCCCHHHHH | 26.04 | 28066266 | |
| 70 | Ubiquitination | PGVLQLGKILNERTV CCHHHHHHHHCCCEE | 53.24 | 22790023 | |
| 70 (in isoform 2) | Ubiquitination | - | 53.24 | 22790023 | |
| 77 (in isoform 2) | Ubiquitination | - | 10.98 | - | |
| 166 (in isoform 2) | Ubiquitination | - | 60.73 | 22790023 | |
| 166 | Ubiquitination | EINRELKKLLVASVG HHHHHHHHHHHHHHC | 60.73 | 22790023 | |
| 173 (in isoform 2) | Ubiquitination | - | 30.98 | - | |
| 265 | Phosphorylation | EQFRQEMTSTQKFLE HHHHHHHHHHHHHHH | 28.06 | 30635358 | |
| 266 | Phosphorylation | QFRQEMTSTQKFLEE HHHHHHHHHHHHHHH | 27.77 | 30635358 | |
| 267 | Phosphorylation | FRQEMTSTQKFLEEL HHHHHHHHHHHHHHH | 26.98 | 30635358 | |
| 356 | Phosphorylation | PVACTESSPDNQFAE CCCCCCCCCCCCCCC | 30.00 | - | |
| 364 | Phosphorylation | PDNQFAESSPTTLLT CCCCCCCCCCCEEEE | 37.88 | 22871156 | |
| 372 | Phosphorylation | SPTTLLTTKKNIGRF CCCEEEEECCCCCCC | 39.74 | 22871156 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GO45_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GO45_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GO45_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TNKS1_HUMAN | TNKS | physical | 26496610 | |
| GORS2_HUMAN | GORASP2 | physical | 26496610 | |
| T11L1_HUMAN | TCP11L1 | physical | 26496610 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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