T11L1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T11L1_HUMAN
• UniProt AC: Q9NUJ3
• Protein Name: T-complex protein 11-like protein 1
• Gene Name: TCP11L1
• Organism: Homo sapiens (Human).
• Sequence Length: 509
• Protein Sequence: MSENLDKSNVNEAGKSKSNDSEEGLEDAVEGADEALQKAIKSDSSSPQRVQRPHSSPPRFVTVEELLETARGVTNMALAHEIVVNGDFQIKPVELPENSLKKRVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLKDVLTTIGEKVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKILVRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSENLDKSN ------CCCCCCCCC	34.88	27486199
16	Phosphorylation	NVNEAGKSKSNDSEE CCCCCHHCCCCCCHH	40.16	28450419
18	Phosphorylation	NEAGKSKSNDSEEGL CCCHHCCCCCCHHHH	53.62	28450419
21	Phosphorylation	GKSKSNDSEEGLEDA HHCCCCCCHHHHHHH	41.62	28450419
38	Ubiquitination	GADEALQKAIKSDSS CHHHHHHHHHHCCCC	53.59	-
42	Phosphorylation	ALQKAIKSDSSSPQR HHHHHHHCCCCCCCC	36.29	26074081
44	Phosphorylation	QKAIKSDSSSPQRVQ HHHHHCCCCCCCCCC	39.54	26074081
45	Phosphorylation	KAIKSDSSSPQRVQR HHHHCCCCCCCCCCC	51.53	26074081
46	Phosphorylation	AIKSDSSSPQRVQRP HHHCCCCCCCCCCCC	29.07	26074081
55	Phosphorylation	QRVQRPHSSPPRFVT CCCCCCCCCCCCEEE	47.42	23401153
56	Phosphorylation	RVQRPHSSPPRFVTV CCCCCCCCCCCEEEH	35.57	22167270
62	Phosphorylation	SSPPRFVTVEELLET CCCCCEEEHHHHHHH	21.35	22617229
69	Phosphorylation	TVEELLETARGVTNM EHHHHHHHHHCCCHH	22.94	23312004
74	Phosphorylation	LETARGVTNMALAHE HHHHHCCCHHHHHCE	23.31	-
99	Phosphorylation	PVELPENSLKKRVKE CCCCCCCHHHHHHHH	39.65	25159151
217	Phosphorylation	PLFREIFSVLDLMKV HHHHHHHHHHHHHHH	27.68	28122231
232	Phosphorylation	DMANFAISSIRPHLM CHHCHHHHHHHHHHH	19.11	24719451
233	Phosphorylation	MANFAISSIRPHLMQ HHCHHHHHHHHHHHH	19.26	25954137
260	Phosphorylation	ILERQPNSLDFVTQW HHHHCCCCHHHHHHH	35.68	29888752
265	Phosphorylation	PNSLDFVTQWLEEAS CCCHHHHHHHHHHHC	17.64	29888752
272	Phosphorylation	TQWLEEASEDLMTQK HHHHHHHCHHHHHHH	34.62	29888752
277	Phosphorylation	EASEDLMTQKYKHAL HHCHHHHHHHCCCCC	29.25	29888752
281	Ubiquitination	DLMTQKYKHALPVGG HHHHHHCCCCCCCCC	29.45	-
293	Phosphorylation	VGGMAAGSGDMPRLS CCCCCCCCCCCCCCC	27.22	28555341
300	Phosphorylation	SGDMPRLSPVAVQNY CCCCCCCCHHHHHHH	20.71	25159151
307	Phosphorylation	SPVAVQNYAYLKLLK CHHHHHHHHHHHHHC	4.59	-
311	Ubiquitination	VQNYAYLKLLKWDHL HHHHHHHHHHCCHHC	38.81	21890473
409	Phosphorylation	LEVSSCLSLCGSSPF HHHHHHHHHHCCCCC	26.41	26074081
413	Phosphorylation	SCLSLCGSSPFTTDK HHHHHHCCCCCCCCH	33.56	26074081
414	Phosphorylation	CLSLCGSSPFTTDKE HHHHHCCCCCCCCHH	14.87	26074081
417	Phosphorylation	LCGSSPFTTDKETVL HHCCCCCCCCHHHHH	37.15	26074081
418	Phosphorylation	CGSSPFTTDKETVLK HCCCCCCCCHHHHHH	45.51	26074081
422	Phosphorylation	PFTTDKETVLKGQIQ CCCCCHHHHHHHHEE	36.56	26074081
433	Phosphorylation	GQIQAVASPDDPIRR HHEEEECCCCCHHHH	23.43	28674151
460	Ubiquitination	YLASGHQKPLPTVPG HHHCCCCCCCCCCCC	42.73	-
470	Phosphorylation	PTVPGGLSPVQRELE CCCCCCCCHHHHHHH	26.71	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T11L1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T11L1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T11L1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.