GLR34_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLR34_ARATH
• UniProt AC: Q8GXJ4
• Protein Name: Glutamate receptor 3.4
• Gene Name: GLR3.4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 959
• Subcellular Localization: Cell membrane; Multi-pass membrane protein. Plastid, chloroplast.
• Protein Description: Glutamate-gated receptor that probably acts as non-selective cation channel, at least in hypocotyls. Can be triggered by Ala, Asn, Gly, Ser and, to a lower extent, Cys and Glu. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. Plays an important role in the calcium-based fast transmission of environmental stress..
• Protein Sequence: MGFLVMIREVSMAKAIRVVLLCVSVLWVVPKECACRSNFSRNSSSSSSSSLRPLRQRPSSVNVGALFTYDSFIGRAAKPAVKAAMDDVNADQSVLKGIKLNIIFQDSNCSGFIGTMGALQLMENKVVAAIGPQSSGIAHMISYVANELHVPLLSFGATDPTLSSLQFPYFLRTTQNDYFQMHAIADFLSYSGWRQVIAIFVDDECGRNGISVLGDVLAKKRSRISYKAAITPGADSSSIRDLLVSVNLMESRVFVVHVNPDSGLNVFSVAKSLGMMASGYVWIATDWLPTAMDSMEHVDSDTMDLLQGVVAFRHYTIESSVKRQFMARWKNLRPNDGFNSYAMYAYDSVWLVARALDVFFRENNNITFSNDPNLHKTNGSTIQLSALSVFNEGEKFMKIILGMNHTGVTGPIQFDSDRNRVNPAYEVLNLEGTAPRTVGYWSNHSGLSVVHPETLYSRPPNTSTANQRLKGIIYPGEVTKPPRGWVFPNNGKPLRIGVPNRVSYTDYVSKDKNPPGVRGYCIDVFEAAIELLPYPVPRTYILYGDGKRNPSYDNLVNEVVADNFDVAVGDITIVTNRTRYVDFTQPFIESGLVVVAPVKEAKSSPWSFLKPFTIEMWAVTGGFFLFVGAMVWILEHRFNQEFRGPPRRQLITIFWFSFSTMFFSHRENTVSSLGRFVLIIWLFVVLIINSSYTASLTSILTIRQLTSRIEGIDSLVTSNEPIGVQDGTFARNYLINELNILPSRIVPLKDEEQYLSALQRGPNAGGVAAIVDELPYIEVLLTNSNCKFRTVGQEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHRKWLNYKHECSMQISNSEDSQLSLKSFWGLFLICGITCFMALTVFFWRVFWQYQRLLPESADEERAGEVSEPSRSGRGSRAPSFKELIKVVDKREAEIKEILKQKSSKKLKSTQSAAGTSQSQHGEIT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	N-linked_Glycosylation	KECACRSNFSRNSSS CHHHCCCCCCCCCCC	21.40	-
42	N-linked_Glycosylation	CRSNFSRNSSSSSSS CCCCCCCCCCCCCCC	45.07	-
46	Phosphorylation	FSRNSSSSSSSSLRP CCCCCCCCCCCCCCC	35.87	23572148
47	Phosphorylation	SRNSSSSSSSSLRPL CCCCCCCCCCCCCCC	35.87	23572148
48	Phosphorylation	RNSSSSSSSSLRPLR CCCCCCCCCCCCCCC	26.37	23572148
49	Phosphorylation	NSSSSSSSSLRPLRQ CCCCCCCCCCCCCCC	35.03	23572148
108	N-linked_Glycosylation	NIIFQDSNCSGFIGT EEEECCCCCCHHHCH	32.06	-
365	N-linked_Glycosylation	VFFRENNNITFSNDP HHCCCCCCEEECCCC	46.38	-
378	N-linked_Glycosylation	DPNLHKTNGSTIQLS CCCCCCCCCCEEEEE	47.42	-
404	N-linked_Glycosylation	MKIILGMNHTGVTGP HHHHHCCCCCCCCCC	27.98	-
443	N-linked_Glycosylation	RTVGYWSNHSGLSVV CCCEEECCCCCCEEE	21.14	-
461	N-linked_Glycosylation	TLYSRPPNTSTANQR HHHCCCCCCCCCCHH	49.71	-
576	N-linked_Glycosylation	GDITIVTNRTRYVDF CEEEEEECCCCCEEC	32.22	-
946	Phosphorylation	KKLKSTQSAAGTSQS HHHHCCCCCCCCCHH	21.85	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLR34_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLR34_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLR34_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HHP4_ARATH	HHP4	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
KIN10_ARATH	KIN10	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
GLR34_ARATH	GLR3.4	physical	24300102
GLR11_ARATH	GLR1.1	physical	24300102
GLR13_ARATH	GLR1.3	physical	24300102
GLR14_ARATH	GLR1.4	physical	24300102
GLR22_ARATH	GLR2.2	physical	24300102
GLR27_ARATH	GLR2.7	physical	24300102
GLR29_ARATH	GLR2.9	physical	24300102
GLR32_ARATH	GLUR2	physical	24300102

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.