GLBL2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLBL2_HUMAN
• UniProt AC: Q8IW92
• Protein Name: Beta-galactosidase-1-like protein 2
• Gene Name: GLB1L2
• Organism: Homo sapiens (Human).
• Sequence Length: 636
• Subcellular Localization: Secreted .
• Protein Sequence: MTTWSLRRRPARTLGLLLLVVLGFLVLRRLDWSTLVPLRLRHRQLGLQAKGWNFMLEDSTFWIFGGSIHYFRVPREYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDLEAFVLMAAEIGLWVILRPGPYICSEMDLGGLPSWLLQDPGMRLRTTYKGFTEAVDLYFDHLMSRVVPLQYKRGGPIIAVQVENEYGSYNKDPAYMPYVKKALEDRGIVELLLTSDNKDGLSKGIVQGVLATINLQSTHELQLLTTFLFNVQGTQPKMVMEYWTGWFDSWGGPHNILDSSEVLKTVSAIVDAGSSINLYMFHGGTNFGFMNGAMHFHDYKSDVTSYDYDAVLTEAGDYTAKYMKLRDFFGSISGIPLPPPPDLLPKMPYEPLTPVLYLSLWDALKYLGEPIKSEKPINMENLPVNGGNGQSFGYILYETSITSSGILSGHVHDRGQVFVNTVSIGFLDYKTTKIAVPLIQGYTVLRILVENRGRVNYGENIDDQRKGLIGNLYLNDSPLKNFRIYSLDMKKSFFQRFGLDKWSSLPETPTLPAFFLGSLSISSTPCDTFLKLEGWEKGVVFINGQNLGRYWNIGPQKTLYLPGPWLSSGINQVIVFEETMAGPALQFTETPHLGRNQYIK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MTTWSLRRRPAR ---CCCCHHHCCHHH	15.20	24719451
13	Phosphorylation	LRRRPARTLGLLLLV HHCCHHHHHHHHHHH	27.55	30576142
86	Ubiquitination	RDRLLKMKACGLNTL HHHHHHHHHCCCCCE	38.65	-
165	Ubiquitination	MRLRTTYKGFTEAVD CCEECCCCCHHHHHH	45.52	21906983
180	Phosphorylation	LYFDHLMSRVVPLQY HHHHHHHHCCEECCC	28.43	27251275
188	Ubiquitination	RVVPLQYKRGGPIIA CCEECCCCCCCCEEE	31.44	-
202	Phosphorylation	AVQVENEYGSYNKDP EEEEECCCCCCCCCC	23.97	25072903
204	Phosphorylation	QVENEYGSYNKDPAY EEECCCCCCCCCCCH	25.32	25072903
205	Phosphorylation	VENEYGSYNKDPAYM EECCCCCCCCCCCHH	23.13	25072903
216	Ubiquitination	PAYMPYVKKALEDRG CCHHHHHHHHHHHCC	26.87	21906983
234	Ubiquitination	LLLTSDNKDGLSKGI EEEEECCCCCCCHHH	59.15	21906983
357	Ubiquitination	EAGDYTAKYMKLRDF CCCHHHHHEEEHHHH	37.77	21906983
502	Ubiquitination	ENIDDQRKGLIGNLY CCCCHHCCCEECEEE	53.05	-
516	Ubiquitination	YLNDSPLKNFRIYSL ECCCCCCCCCEEEEE	58.38	21906983
522	Phosphorylation	LKNFRIYSLDMKKSF CCCCEEEEEECCHHH	18.60	24719451
528	Phosphorylation	YSLDMKKSFFQRFGL EEEECCHHHHHHHCC	26.27	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLBL2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLBL2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLBL2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPTB1_HUMAN	SPTB	physical	28514442
GLP3L_HUMAN	GOLPH3L	physical	28514442
GRP78_HUMAN	HSPA5	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.