G3BP_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: G3BP_SCHPO
• UniProt AC: O94260
• Protein Name: Putative G3BP-like protein
• Gene Name: nxt3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 434
• Protein Description: Probable scaffold protein that may be involved in mRNA transport..
• Protein Sequence: MTAENATLLEPVLGKDEIGWMFVQEYYTYLNKEPNRLHCFYTKKSTLIHGDEGESISLCHGQQEIHNKILDLDFQNCKVLISNVDSLASSNGGIVIQVLGEMSNKGKLSRKFAQTFFLAEQPNGYFVLNDIFRFLREDVEEEEESPDAVEKEKKDVASEPYVNGVQSQEHLPSAKEEGHYQDPAATENNFATAALISNETDSLNQATLAVPEEPVIQVTEASVPSFVSQQENQLQDEALTSNSKNADAIGASDANVATAPKSWADLIARNHPDVKSQASVSSTASTTGQTVKGVNADQTQQPTAPYTQSNELLETSVFVKNIPPETSDVSLKSAMSIFGPVKAIEFARRKGTAYVDFVNHECVQLALNKKTLQINNATLNIEERRRLFSGKFNKSGDKKSNDNYNGMKRNFRKGNRGAFDGRSKEVTTSKKQNN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
145	Phosphorylation	DVEEEEESPDAVEKE CHHHHHHCCCHHHHH	31.21	28889911
158	Phosphorylation	KEKKDVASEPYVNGV HHHHCCCCCCCCCCC	38.66	21712547
161	Phosphorylation	KDVASEPYVNGVQSQ HCCCCCCCCCCCCCC	11.51	28889911
167	Phosphorylation	PYVNGVQSQEHLPSA CCCCCCCCCCCCCCC	34.82	28889911
173	Phosphorylation	QSQEHLPSAKEEGHY CCCCCCCCCCHHCCC	59.33	21712547
252	Phosphorylation	NADAIGASDANVATA CCCHHCCCCCCCCCC	31.85	25720772
276	Phosphorylation	RNHPDVKSQASVSST HHCCCHHCCCEECCC	30.72	25720772
279	Phosphorylation	PDVKSQASVSSTAST CCHHCCCEECCCCCC	18.20	25720772
281	Phosphorylation	VKSQASVSSTASTTG HHCCCEECCCCCCCC	21.34	24763107
282	Phosphorylation	KSQASVSSTASTTGQ HCCCEECCCCCCCCC	26.32	25720772
283	Phosphorylation	SQASVSSTASTTGQT CCCEECCCCCCCCCE	19.68	29996109
285	Phosphorylation	ASVSSTASTTGQTVK CEECCCCCCCCCEEC	26.96	25720772
286	Phosphorylation	SVSSTASTTGQTVKG EECCCCCCCCCEECC	32.26	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of G3BP_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of G3BP_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of G3BP_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBP3_SCHPO	ubp3	physical	22328580
RL3B_SCHPO	rpl302	physical	22328580
RL4B_SCHPO	rpl401	physical	22328580
RL13_SCHPO	rpl13	physical	22328580
RS3A1_SCHPO	rps101	physical	22328580
RS9A_SCHPO	rps901	physical	22328580

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-145, AND MASSSPECTROMETRY.
PubMed: 18257517